睡眠・覚醒リズムと体温リズムの脱同調及び再同調過程についての基礎的研究

睡眠/觉醒节律和体温节律去同步和重新同步过程的基础研究

• 批准号: 05710058
• 负责人: 佐々木 由香
• 金额: $ 0.58万
• 依托单位: Waseda University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Encouragement of Young Scientists (A)
• 财政年份: 1993
• 资助国家: 日本
• 起止时间: 1993 至 无数据
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-05710058/
• 关键词: 睡眠・覚醒リズム; 体温リズム; 脱同調; サーカディアンリズム

本研究の目的は、睡眠・覚醒リズムと体温リズムの脱同調過程についての基礎的研究であった。そのために、体温リズムの下降期や上昇期などの異なる位相に睡眠期を設定し、体温リズムの振幅変化や位相変化(最高温・最低温期の時刻的変化)の程度、作業能率、気分や眠気への影響、及び睡眠構造の変化を測定した。以下に具体的に手続を述べる。被験者を4名用いて被験者内で4条件を設定し、1条件に12日間、のべ144日間必要とした。実験期間中は、被験者の行動量と直腸温を連続的に測定した。被験者は、実験第1・2・3日目は、睡眠時刻(00:00-07:30)のみ統制し、日中の行動は自由とした。第4日目は睡眠期(00:00-07:30)のみ実験室で生理的指標(睡眠ポリグラフなど)を記録した。第5・6・7日目に連続72時間の実験室拘束を行い、連続的に生理的指標を記録した。拘束中の睡眠期はそれぞれ、第5日目は00:00から07:30、6日目は、4条件によって異なり、条件1)は直腸温の最低温期(00:00-07:30)、条件2)同上昇期(05:30-13:00)、条件3)同最高温期(11:30-09:00)、条件4)同下降期(16:00-23:30)に設定し、7日目は直腸温の位相反応量を調べるため、直腸温に影響を与える可能性のある睡眠期を設定しなかった(断眠日)。第5・6・7日において覚醒期は合計56時間あるが、覚醒中は1時間ごとに20分間の清新さ行を行った。第8・9日は回復日として、4日目同様、睡眠期のみ実験室で記録した。第10・11・12日は、第1・2・3日と同様に睡眠期のみ統制された日常生活を送った。実験は終了し、現在までに直腸温データの一部が解析済みである。その結果連続実験室拘束日の直腸温リズムは条件1)-4)の間で、振幅・平均値・最低温の出現時刻が異なり、睡眠・覚醒リズムと体温リズム間の交互作用の存在が示唆された。今後、作業能率、気分や眠気への影響、及び睡眠構造の変化について検討をすすめる予定である。

The purpose of this study is to study the relationship between body temperature and the basis of the study of sleep and wakefulness. During the period of decline of body temperature, the setting of phase and phase of body temperature, the amplitude of amplitude and phase of body temperature, the degree of change of amplitude and phase (the peak of the highest temperature and the lowest temperature), the energy rate, the sleep cycle, and the sleep cycle. The following is a specific manual description. Four of the victims use the 4 conditions to set the settings, 1 the conditions are within 12 days, and the other is within 144 days. During the period of purchase, the amount of activity of the victim and the victim shall be measured and measured directly. The victims were caught on the 123rd day, the sleep time (00:00-07:30) was monitored, and the exercise was carried out freely during the day and the middle of the day. On the 4th day, during the sleep period (00:00-07:30), the physiological fingers of the room were recorded. On the 567th day, during 72 hours of contact, the physical indicators of the connection were recorded in the detention room. During sleep restriction, 00:00 on the 5th day, 07:30 on the 5th day, 4 conditions on the 6th, condition 1) the lowest temperature period (00:00-07:30), condition 2) the same period as the previous cycle (05:30-13:00), condition 3) the same maximum temperature period (11:30-0900), condition 4) the same falling period (1600-2340) setting, condition 3) the same maximum temperature period (1600-23900) On the 7th, the temperature of the eyes is in the opposite direction, and the temperature of the temperature and the possibility of the temperature are measured. The sleep period is set to sleep (sleep day). On the 567 day, there were 56 hours of waking up, 1 hour of waking up and 20 minutes of refreshing. On the 8th day, I went back to the morning, and on the 4th, I did the same thing, and during the sleeping period, I recorded a lot of time in the room. On the 10th, 11th, 12th and 13th day, they were sent to their daily lives during the same period of sleep. I'm sorry, but now I'm going to tell you how to analyze it one by one. Results the results show that there is an instigating effect on the interaction between temperature and temperature in the connecting room, the daily direct temperature test condition 1)-4) the peak temperature, the amplitude average minimum temperature temperature and the interaction between the temperature temperature of sleep wakefulness and wakefulness. In the future, the energy rate, sleep rate, and sleep rate will be determined.