Optical biomicroscopy in fundus diseases
Optical biomicroscopy in fundus diseases
批准号:
07407048
负责人:
SHIMIZU Koichi
金额:
$8.96万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
1995
资助国家:
日本
项目状态:
已结题
起止时间:
1995 至 1997
中文摘要
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英文摘要
Scanning laser ophthalmoscope (SLO) allows an enhanced image of superficial and deeper retinal layr observed by argon and helium-neon laser respectively.Optical coherence tomography (0CT) provides an cross-sectional image of the retina with 10-20 um resolution. We studied "the histology in vivo" of various fundus diseases with OCT alone or with OCT and SLO.1) SLO showed an elevation of the Henle's fiber layr is an initial change in macular hole development. It was observed as the retinoschisis at the fovea with OCT.Operculua was formed by thin retinal tissue detached from the retinal pigment epithelium at the fovea. 2) SLO clearly demonstrated the epiretinal membrane and surperficial retinal folds by argon and helium-neon laysers. OCT revealed unexpected retinal thickning particularly at the outer retina. 3) OCT demonstrated the three pattern of macular edema which included a sponge-like swelling, cystoid edema and serous retinal detachment. 4) The cross-sectional image of age-related macular degeneration showed the increased reflectivity of subretinal pigment epithelial space according to the evolution of the lesion from RPE detachment to the disciform degeneration with choroidal neovascularization. 5) OCT showed decreased reflectivity of the retina in heigh myope with posterior staphloma. As elongation of the optical axis, retinoschisis may develop at the macula. 6) OCT demonstrated the detached retina may develop tissue swelling.
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Role of Cytokines in mediating of Ischemia/Reperfusion Injury in Liver.
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Basic study for non-invasive measurement of internal function of animal body with light
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Basic Study for Imaging Internal Structure of Biological Body by Optical Technique
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