Development of novel membrane type artificial lung having controlled surface morphology
具有可控表面形态的新型膜式人工肺的开发
基本信息
- 批准号:07558131
- 负责人:
- 金额:$ 3.46万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (B)
- 财政年份:1995
- 资助国家:日本
- 起止时间:1995 至 1996
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Organosilicon-containing polystirene/poly (2-hydroxyethyl methacrylate)block copolymers were prepared by an anionic living polymerization technique. The obtained block copolymer showed unique thermodynamic properties. Especially, the block copolymer which possess only 10 mol% of poly (Si-stirene) segment showed very low glass transition temperature (Tg=10゚C) though both segments exhibit the fairly high Tgs (150 and 70゚C). The high flexibility of the copolymer chain caused extremely high blood compatibility. The obtained block copolymers also shows high gas exchange ability not only dry but also wet conditions due to the introduction of two organosilicon groups in each monomer unit. By construction of this film using this block copolymer on PP microporous membrane, the high performance membrane which possess both blood compatibility and high gas permeability was obtained.
采用阴离子活性聚合技术合成了含有机硅的聚苯乙烯/聚甲基丙烯酸羟乙酯嵌段共聚物。所得嵌段共聚物显示出独特的热力学性质。特别是,仅具有10摩尔%的聚(Si-苯乙烯)链段的嵌段共聚物显示出非常低的玻璃化转变温度(Tg=10 ℃),尽管两个链段都显示出相当高的Tg(150和70 ℃)。共聚物链的高柔性导致极高的血液相容性。由于在每个单体单元中引入了两个有机硅基团,所得到的嵌段共聚物无论在干态还是湿态都显示出高的气体交换能力。用该嵌段共聚物在聚丙烯微孔膜上成膜,得到了兼具血液相容性和高透气性的高性能膜。
项目成果
期刊论文数量(30)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
長崎幸夫: "A creation of an intelligent surface-The design of a reactive surface with stimuli-sensitivity toward temperature and pH-" Plenum(in press),
Yukio Nagasaki:“智能表面的创造 - 对温度和 pH 值具有刺激敏感性的反应表面的设计 -” Plenum(正在印刷中),
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S.Cammas, A.Harada, Y.Nagasaki, K.Kataoka: "Poly (ethylene oxide-co-beta-benzyl-L-aspartate) block copolymers : Influence of the poly (ethylene oxide) block on the conformationof the poly (beta-benzyl-L-aspartat) segment in organic solvents" Macromolecule
S.Cammas、A.Harada、Y.Nagasaki、K.Kataoka:“聚(环氧乙烷-共-β-苄基-L-天冬氨酸)嵌段共聚物:聚(环氧乙烷)嵌段对聚(环氧乙烷)构象的影响”
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長崎幸夫: "Rubber elasticity transition of poly(silamine) induced by ionic interactions" Macromolecular Rapid Communications. 17(1). 51-58 (1995)
Yukio Nagasaki:“离子相互作用诱导的聚(硅胺)橡胶弹性转变”《高分子快速通讯》17(1)(1995)。
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Y.Nagasaki: "A creation of an intelligent surface" Trends in Polymer Science. 4(2). 59-64 (1996)
Y.Nagasaki:“智能表面的创造”聚合物科学趋势。
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- 影响因子:0
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Y.Nagasaki, Y.Hashimoto, M.Kato, T.Kimijima: "Gas permeation properties of organosilicon-containing polystirenes." Journal of Memrane Science. 110 (1). 91-97 (1996)
Y.Nagasaki、Y.Hashimoto、M.Kato、T.Kimijima:“含有机硅的聚苯乙烯的气体渗透性能。”
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NAGASAKI Yukio其他文献
NAGASAKI Yukio的其他文献
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{{ truncateString('NAGASAKI Yukio', 18)}}的其他基金
Design of injectable gel with NO releasing properties and its application
具有NO释放性能的注射凝胶的设计及其应用
- 批准号:
16K15628 - 财政年份:2016
- 资助金额:
$ 3.46万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
Design of Novel Biomaterials which Scavenge Reactive Oxygen Species and Their Applications
清除活性氧的新型生物材料的设计及其应用
- 批准号:
25220203 - 财政年份:2013
- 资助金额:
$ 3.46万 - 项目类别:
Grant-in-Aid for Scientific Research (S)
A Challenge to Cerebral Diseases by Nanomedicine
纳米医学对脑疾病的挑战
- 批准号:
22659008 - 财政年份:2010
- 资助金额:
$ 3.46万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
Design of Biomaterials Platform which responds to Oxidative Stress
响应氧化应激的生物材料平台设计
- 批准号:
21240050 - 财政年份:2009
- 资助金额:
$ 3.46万 - 项目类别:
Grant-in-Aid for Scientific Research (A)
Bionanosensing based on Bio-frontier Surface
基于生物前沿表面的生物纳米传感
- 批准号:
18200033 - 财政年份:2006
- 资助金额:
$ 3.46万 - 项目类别:
Grant-in-Aid for Scientific Research (A)
Design for Novel Stimuli-Sensitive Hydrogel, Polysilamine, and its Materials Design
新型刺激敏感水凝胶聚硅胺的设计及其材料设计
- 批准号:
14350502 - 财政年份:2002
- 资助金额:
$ 3.46万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Creation of High Performance Biocompatible Surface by Surface modification agent which Constructs High Density Tethered Chains
通过构建高密度系链的表面改性剂创建高性能生物相容性表面
- 批准号:
10558139 - 财政年份:1998
- 资助金额:
$ 3.46万 - 项目类别:
Grant-in-Aid for Scientific Research (B).
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