The Experimental Study of the Venous Drainage through theBone Marrow at Replantation of the Amputated Digits and free tissue transfer.

断指再植及游离组织移植时骨髓静脉引流的实验研究。

• 批准号: 07671601
• 负责人: TANAKA Katsumi
• 金额: $ 1.54万
• 依托单位: NAGASAKI UNIVERSITY MEDICINE
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1996
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07671601/
• 关键词: fingertip amputation; replantation; venous drainage; bone marrow; free flap transfer

Venous drainage is an important factor for the success of the replantation of the amputated digits, especially at the level of distal phalanx. However, venous drainage cannot be always reconstructed, because the vein is not searched and is too small to suture etc. In this study, the venous drainage through the bone marrow is seemed to be useful and significant while the new subcutaneous vein.The amputated limbs are observed skin color and the blood flow of them are measured with a laser Doppler flow meter. Dye injection study and radioisotope perfusion study of the bone marrow are perfomed. The groups of the bone marrow with continuity are almost survival. It is suggested that the bone marrow is imporatant for the venous drainage. We have had many clinical cases which been replanted digits amputated at the distal phalanx level and have experienced several successful cases without venous reconstruction. Most of them were excised the distal phalangeal joint cartilage and both of the phalangeal bones were fixed using only single sraight wire with the least damage possible at replantation.There are a few reports which are described significance of the bone marrow for the venous drainage sysytem and there is no report which is investigated experimentally. It was suggested that the bone marrow was imporatant for the venous drainage, especially at the immediately-phase and early-phase after operation until the regeneration of the subcutaneous venous drainage system.

静脉引流是断指再植成功的重要因素，尤其是远端指骨水平。然而，静脉引流不能总是重建，因为静脉没有被搜索到，太小而无法缝合等。在本研究中，通过骨髓的静脉引流似乎是有用的和有意义的，而新的皮下静脉。观察截肢的皮肤颜色，并用激光多普勒流量计测量其血流量。进行了骨髓的染料注射研究和放射性同位素灌注研究。骨髓有连续性的群体几乎都是存活的。这表明骨髓对于静脉引流很重要。我们有许多在远端指骨水平截肢再植手指的临床病例，并且经历了一些无需静脉重建的成功病例。大多数都是切除远端指骨关节软骨，仅用单根直丝固定两根指骨，再植时损伤最小。有一些报道描述了骨髓对于静脉引流系统的重要性，但没有经过实验研究的报道。提示骨髓对于静脉引流至关重要，尤其是术后即刻和早期直至皮下静脉引流系统再生。

项目成果

Yano H,Nishimura G,Kaji S,Murakami R,Fujii T: "A Clinical and Histologic Comparison Between Temporoparietal and Scapular Fascial Flaps" Plast Reconst Surg. 95. 452-462 (1995)

Yano H，Nishimura G，Kaji S，Murakami R，Fujii T：“颞顶筋膜瓣和肩胛筋膜瓣之间的临床和组织学比较”整形重建外科。

Katsumi Tanaka et al: "Experimental Study of Venous Drainage through the Bone Marrow on Repalantation of Amputated Digits" Transactions of the 11th Congress of the international Confederation of Plastic,Reconstructive and Aesthetic Surgery. 100-100 (1995)

Katsumi Tanaka 等人：“截肢手指再植时通过骨髓进行静脉引流的实验研究”国际整形、重建和美容外科联合会第 11 届大会会刊。