Development of Implant Biomaterials by Ceramic Coating Technologies

我们已经通过一些陶瓷涂层技术开发了种植生物材料，这些技术主要是通过电泳沉积(EPD)、溅射(SP)和等离子喷涂(PS)方法进行的。我们的新的电沉积方法成功地制备了由粘附性磷灰石-磷酸钙涂层和生物活性多孔磷灰石-石墨表面组成的复合涂层。在SPT方法中，我们确定了钙磷比低于羟基磷灰石的钙磷酸盐玻璃靶材的使用。该方法也适用于金属基材的水热退火涂层。使用羟基磷灰石和磷酸三钙的PS膜，通过细胞培养评价了两者之间的生物相容性，表明后者由于其溶解性而似乎具有很好的生物相容性。我们还研究了极化辅助骨状晶体在这些薄膜上的生长。

We have developed implant biomaterials by some ceramic coating technologies, which were mainly undertaken by electrophoretic deposition (EPD) , sputtering (SP) , and plasma spray (PS) methods. Our new EPD method successfully produced composite coatings, consisting of the layrs of adhersive apatite-calcium phosphate and bioactive porous surface of apatite-graphite. In SPT method, we established the use of glass targets of calcium phosphates with lower Ca/P ratios than hydroxyapatite. This method was also applied to the coating of metal substrates by hydrothermal annealing. Using PS films of hydroxyapatite and tri-calcium phosphate, the biocompatibility between the two was evaluated by cell cultivation, suggesting the latter seems somehow excellent to the latter because of the solbility. We also studied the poling-aided bone-like crystal growth on these films.