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Development of Implant Biomaterials by Ceramic Coating Technologies

Development of Implant Biomaterials by Ceramic Coating Technologies
利用陶瓷涂层技术开发植入生物材料
批准号:
08555219
负责人:
YAMASHITA Kimihiro
金额:
$8.26万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
1996
资助国家:
日本
项目状态:
已结题
起止时间:
1996 至 1997

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项目成果

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中文摘要
翻译
我们已经通过一些陶瓷涂层技术开发了种植生物材料,这些技术主要是通过电泳沉积(EPD)、溅射(SP)和等离子喷涂(PS)方法进行的。我们的新的电沉积方法成功地制备了由粘附性磷灰石-磷酸钙涂层和生物活性多孔磷灰石-石墨表面组成的复合涂层。在SPT方法中,我们确定了钙磷比低于羟基磷灰石的钙磷酸盐玻璃靶材的使用。该方法也适用于金属基材的水热退火涂层。使用羟基磷灰石和磷酸三钙的PS膜,通过细胞培养评价了两者之间的生物相容性,表明后者由于其溶解性而似乎具有很好的生物相容性。我们还研究了极化辅助骨状晶体在这些薄膜上的生长。
英文摘要
We have developed implant biomaterials by some ceramic coating technologies, which were mainly undertaken by electrophoretic deposition (EPD) , sputtering (SP) , and plasma spray (PS) methods. Our new EPD method successfully produced composite coatings, consisting of the layrs of adhersive apatite-calcium phosphate and bioactive porous surface of apatite-graphite. In SPT method, we established the use of glass targets of calcium phosphates with lower Ca/P ratios than hydroxyapatite. This method was also applied to the coating of metal substrates by hydrothermal annealing. Using PS films of hydroxyapatite and tri-calcium phosphate, the biocompatibility between the two was evaluated by cell cultivation, suggesting the latter seems somehow excellent to the latter because of the solbility. We also studied the poling-aided bone-like crystal growth on these films.
期刊论文(75)
专著(0)
科研奖励(0)
会议论文
K.Yamashihta: "Electrophoretic Coating of Muiti-layered Apatite Composite on Alumina Ceramics" J.Biomed.Mat.Res.(Appl.Biomat.). (in press).
K.Yamashihta:“氧化铝陶瓷上多层磷灰石复合材料的电泳涂层”J.Biomed.Mat.Res.(Appl.Biomat.)。
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通讯作者:
K.Yamashihta: "Fabrication of Green Films of Single-and Multi-Component Ceramic Composites by ElectrophoreticDeposition Technique" J.Mat.Sci.32. 6661-6664 (1997)
K.Yamashihta:“通过电泳沉积技术制备单组分和多组分陶瓷复合材料的绿色薄膜”J.Mat.Sci.32。
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M.Matsuda: "Novel Electrochemical Route for Reduction of Superconducting Bi_2Sr_2CaCu_2O_<8+>" J.Am.Ceram.Soc.80・4. 1032-1034 (1997)
M.Matsuda:“用于还原超导 Bi_2Sr_2CaCu_2O_<8+> 的新电化学路线”J.Am.Ceram.Soc.80・4 (1997)。
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K.Yamashita: "Microstructural Effects on Conduction Properties of Na_5YSi_4O_<12>-Type Glass-Ceramic Na^+-Fast Ionic Conductors" J.Electrochem.Soc.143・7. 2180-2186 (1996)
K.Yamashita:“Na_5YSi_4O_<12>型玻璃陶瓷Na^+-快离子导体的微观结构影响”J.Electrochem.Soc.143・7(1996)。
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