Biomechanics on the mechanical adaptation of biological tissues and its applications to engineering

生物组织机械适应的生物力学及其工程应用

• 批准号: 08650110
• 负责人: YAMAMOTO Noritaka
• 金额: $ 1.41万
• 依托单位: Ritsumeikan University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1996
• 资助国家: 日本
• 起止时间: 1996 至 1997
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08650110/
• 关键词: Biomechanics; Mechanical adaptation; Biological tissue; Exercise; Patellar tendon; Mechanical properties; Tension; In vivo measurement

1.The in vivo force applied to the patellar tendon (PT) of rat during treadmill running was measured using an implantable force transducer. The transducer consisted of a slightly curved stainless steel plate on which a strain gauge was bonded. The mean peak force during running at the speed of 0.6km/h on a level was 11.3N and the peak stress was 6MPa. The mean peak force increased by 22% with increase in the speed from 0.6 to 1.0km/h, but the increase was not significant. There were no significant differences in the peak force among level running and inclined running on the slopes of 15 and 30 degrees.2.After running at 0.6km/h on a level, rats were sacrificed and tensile tests were performed on their PTs. There were no significant differences in the dimensions and mechanical properties. These results indicate that the cyclic loading of the peak force of 11.3 N (the peak stress of 6 MPa) did not change the mechanical properties of PT.3.The cyclic load was applied to rat patellar tendon in vitro. The mechanical strength was unchanged by the loading of the peak stress of 9 MPa but significantly decreased by that of 10.5 MPa. These values of peak stress were 1.5 and 1.75 times of that applied to the PT of rat during running at 0.6 km/h on a level, respectively.

1.采用植入式力传感器测量大鼠在体髌腱在跑台运动中的受力。传感器由一个稍微弯曲的不锈钢板组成，其上粘合有一个应变计。在水平上以0.6km/h速度运行时，平均峰值力为11.3N，峰值应力为6 MPa。在0.6 ~ 1.0km/h的速度范围内，平均峰值力随速度的增加而增加22%，但增加不显著。在15 °和30 °坡度上，水平跑和倾斜跑的峰值力无显著性差异。2.大鼠在水平跑后，以0.6km/h的速度处死，对PT进行拉伸实验。尺寸和机械性能无显著差异。这些结果表明，峰值力为11.3N（峰值应力为6 MPa）的循环载荷并没有改变PT的力学性能。3.对离体大鼠髌腱施加循环载荷。机械强度在9 MPa的峰值应力下没有变化，但在10.5MPa的峰值应力下显著降低。这两个峰值应力分别是大鼠0.6km/h水平跑时PT的1.5倍和1.75倍。

项目成果

高内 正美, 山本 憲隆: "ラット膝蓋腱に作用する張力の生体内計測" 日本機械学会第10回バイオエンジニアリング講演会講演論文集. 118-119 (1998)

Masami Takauchi、Noritaka Yamamoto：“作用于大鼠髌腱的张力的体内测量”日本机械工程师学会第十届生物工程会议论文集 118-119（1998）。

M.Takauchi and N.Yamamoto: "In Vivo Measurement of Tension in Rat Patellar Tendon" Proc.10th Bioengineering Conference. 118-119 (1998)

M.Takauchi 和 N.Yamamoto：“大鼠髌腱张力的体内测量”Proc.10th 生物工程会议。

N.Yamamoto, M.Takauchi: "In Vivo Measurement of Patellar Tendon Force in Rat during Running on a Treadmill" Proc.3rd World Congress of Biomechanics. ((発表予定))

N.Yamamoto、M.Takauchi：“在跑步机上跑步时大鼠髌腱力的体内测量”Proc.第三届世界生物力学大会（（待提交））

N.Yamamoto and M.Takauchi: "In Vivo Measurement of Patellar Tendon Force in Rat during Running on a Treadmill" Proc.3rd World Congress of Biomechanics. (1998)

N.Yamamoto 和 M.Takauchi：“在跑步机上跑步时大鼠髌腱力的体内测量”Proc.第三届世界生物力学大会。

N.Yamamoto, M.Takauchi: "In Vivo Measurement of Patellar Tendon Force in Rat during Running on a Treadmill" Proc.Third World Congress of Biomechanics. (発売予定).

N. Yamamoto，M. Takauchi：“在跑步机上跑步时大鼠髌腱力的体内测量”，第三届世界生物力学大会（待发布）。