FLUORIDE ANALYSIS IN INFANT FOODS AND ESTIMATION OF DAILY FLUORIDE INTAKES

本研究的目的是分析商业婴儿食品中的氟化物含量，并估计3 -9个月大婴儿的每日氟化物摄入量（DEl）。氟化物在人体内的生物利用度是确定局部和系统应用氟化物预防口腔疾病效果的关键因素。食品中的生物利用度被认为取决于其电离、结合形式及其与共存成分的关系。本研究的另一个目的是考察氟化物与各种食物中所含的一些矿物质的酸溶解和电离的生物利用度。收集了10种奶粉和39种其他婴儿食品进行氟化物测定。采用hmds -微扩散法（Koga et a1, 1994）从婴儿食品中分离氟化物。氟的溶解用蒸馏水和0。O1M HCI和0.1M HCl。这些样品是用一些高氟化物的食物做的。在…More nts配方奶粉中发现的氟化物含量在0.37-1之间。Oppm（平均氟化物含量：0.595 ppm）和其他婴儿食品的范围从0。10ppm至0.30 ppm即食氟化物含量。3-4个月、5-6个月和7-8个月的婴儿每日氟化物摄入量估计分别为0.175、00.201和0.266毫克/天。3-9月龄婴儿每日氟摄入量为0.024-0.029mg/kg。这一结果表明，每日从商品婴儿食品中摄取的氟化物可在最佳氟化物水平0。O7mgF/kg在Ophaug论文（1985）中报道。本研究调查的婴儿食品中氟化物浓度较低，为0.21 ~ 2.9lppm，其氟溶出率为25.4% ~ 74.7%，其中0。O1M盐酸。南极磷虾肌肉中的氟化物与水的高度电离可能是松散结合的，并且与镁的浓度高度相关，镁的溶解与氟化物在pH2-7缓冲液中的溶解非常相似。粗级绿茶的氟溶出率在水和0.1M HCl中分别约为60%和45%。因此，结果反映了绿茶中的氟化物可能存在松散和紧密的结合。与其他食物相比，骨粉和干沙丁鱼的钙含量更高。由于干沙丁鱼和骨粉的氟化物和钙的溶解与ph值密切相关，这表明它们样品中的氟化物可能与钙紧密结合。结果表明，相对于钙含量，镁含量对氟化物的生物利用度的影响更大。少

The Purpose of this study was to analyze the fluoride content in commercial infant foods and estimate of daily fluoride intake (DEl) during 3 -9 months old. Also the bioavailability of fluoride in human body is key factor to ascertain locally and systemically the effect of fluoride applications for the prevention of oral diseases. The bioavailability in foods is considered to depend on its ionization, bound form and its relationship to coexisting components. The other purpose of this study was to examine acid dissolution and ionization of fluoride in terms of bioavalability with some minerals contained in various foods. Ten kinds of powdered milk and 39 kinds of other infant foods were collected for determination of fluoride. HMDS-microdiffusion method (Koga et a1, 1994) was used to separate fluoride from infant foods. The dissolution of fluoride was performed with distilled water and 0.O1M HCI and 0.1M HCl. The samples were used of some high fluoride foods. Fluoride content found infa … More nts formula were ranged from 0.37-1.Oppm(mean fluoride content : 0.595 ppm) and other infant foods were ranged from 0.l0ppm to O.30ppm ready-to-feed fluoride content. Daily fluoride intake of infants estimates 0.175, 00.201 and 0.266mg/day for 3-4months, 5-6 months and 7-8months old, respectively. Daily fluoride intake of infants per kg was ranged 0.024-0.029mg/kg for 3-9 months old. This result indicate that daily fluoride intake from commercial infant foods could be within optimal fluoride level of 0.O7mgF/kg in Ophaug paper(1985) reported. Fluoride in infant foods investigated in this study had low concentrations of 0.21-2.9lppm and their fluoride dissolution rates were ranged from 25.4 to 74.7% with 0.O1M HCl. Fluoride in Antarctic Krill muscle might be loosely bound because of its high ionization with water and highly associated with the concentration of magnesium and the magnesium dissolution was very similar to that of fluoride with pH2-7 buffers. Fluoride dissolution rates of green tea (coarse grade) showed approximately 60% with water and 45% with 0.1M HCl, respectively. Therefore the results reflected that fluoride of green tea may exist both loosely and tightly bound. Bone meal and dried sardines contained higher calcium concentrations compared with other foods. As fluoride and calcium dissolutions of dried sardines and bone meal were strongly pH-dependent, it indicated that fluoride in their samples was presumed tightly bound to calcium. The results suggested that the bioavailability of fluoride be much influenced by the contents of magnesium in comparison with calcium with regard to ionization of fluoride in foods. Less