Research for prediction of cervical lymph node metastasis in tongue cancer using fuzzy inference

模糊推理预测舌癌颈部淋巴结转移的研究

• 批准号: 10470436
• 负责人: NAGATA Tetsuji
• 金额: $ 2.24万
• 依托单位: KYUSHU UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 1998
• 资助国家: 日本
• 起止时间: 1998 至 1999
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10470436/
• 关键词: fuzzy inference; tongue cancer; lymph node metastasis; prediction; multivariate analysis; 口腔癌; リンパ節転移; ファジイ推論

The purpose of this study was to predict lymph node metastasis in tongue cancer. The subjects were 137 patients with squamous cell carcinoma of the tongue who had been treated at our department during the 20-year period from 1971 through 1990. We first used multivariate analysis and then fuzzy inference to assess the accuracy of these methods for predicting lymph node metastasis. Based on the results of the chi-square test and a correlation matrix, T category, N category, keratinization, mitosis and mode of invasion were selected as parameters for multivariate analysis. Among the 137, 104 were correctly identified by this multivariated analysis. For the prediction using fuzzy inference, the patients were first divided into two groups : those treated surgically and those given radiotherapy. Three items, i.e., tumor size, keratinization and mode of invasion were used for analysis. Then, an "If-Then rule" was applied to each of the two groups. The accurate rate of the 137 cases was 78.1%, sensitivity was 69.0%, and specificity was 84.8%. These figures exceeded the accuracy obtained by the multivariate analyses. Fuzzy inference appears to be useful for predicting lymph node metastasis.

本研究的目的是预测舌癌的淋巴结转移。研究对象为1971年至1990年20年间在我科接受治疗的137名舌鳞状细胞癌患者。我们首先使用多变量分析，然后使用模糊推理来评估这些方法预测淋巴结转移的准确性。根据卡方检验的结果和相关矩阵，选择T类、N类、角质化、有丝分裂和侵袭模式作为多变量分析的参数。在 137 个样本中，通过多变量分析正确识别出 104 个。为了使用模糊推理进行预测，患者首先被分为两组：接受手术治疗的患者和接受放射治疗的患者。采用肿瘤大小、角化程度和侵袭方式三个项目进行分析。然后，“If-Then 规则”应用于两组。 137例的准确率为78.1%，敏感性为69.0%，特异性为84.8%。这些数字超出了多变量分析获得的准确性。模糊推理似乎对于预测淋巴结转移有用。

项目成果

Tetsuji NAGATA: "Prediction of cervical lymph node metastasis in carcinoma of the tongue using fuzzy inference"Biomedical soft computing and human sciences. vol6. 51-59 (2000)

Tetsuji NAGATA：“利用模糊推理预测舌癌颈部淋巴结转移”生物医学软计算和人文科学。

Tetsuji NAGATA: "Prediction of cervical lymph node metastasis in carcinoma of the tongue using fuzzy inference and its problem"Proceeding of the 13th annual meeting of biomedical fuzzy system association. Vol1. 91-97 (2000)

Tetsuji NAGATA：“利用模糊推理预测舌癌颈部淋巴结转移及其问题”生物医学模糊系统协会第13届年会论文集。

Tetsuji.NAGATA: "Prediction of cervical lymph node metastasis in carcinoma of the tongue using fuzzy inference"Biomedical soft computing and human sciences. 6. 51-59 (2000)

Tetsuji.NAGATA：“使用模糊推理预测舌癌颈部淋巴结转移”生物医学软计算和人文科学。

長田哲次: "ファジィ推論を用いた舌癌リンパ節転移予測"バイオメディカル・ファジィ・システム学会第13会年次大会講演論文集. 1. 91-97 (2000)

Tetsuji Osada：“使用模糊推理预测舌癌淋巴结转移”生物医学模糊系统学会第 13 届年会论文集 1. 91-97 (2000)。