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A Magnetic Fluid-Driven Artificial Heart

磁流体驱动的人造心脏

基本信息

批准号：
10680800
负责人：
MITAMURA Yoshinori
金额：
$ 2.43万
依托单位：
HOKKAIDO UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1998
资助国家：
日本
起止时间：
1998 至 1999
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10680800/
关键词：
Artificial Heart Magnetic Fluid 磁性流体

项目摘要

A variety of implantable artificial hearts have been studied. They, however, have a common drawback of utilizing bearings and a complicated driving mechanism. A magnetic fluid actuator, on the other hand, drives magnetic fluids directly simply by applying magnetic field and does not require a bearing. Feasibility of a magnetic fluid-driven artificial heart was studied.Two ring solenoids with an air gap of 10 mm were arranged near an acrylic tube (10 mmOD, 7.4 mmID). A small balloon (volume: 2mL) was connected to the both ends of the acrylic tube. The balloon was encased in a rigid box that had an inlet and outlet port. The acrylic tube and the balloons were filled with Fluorinert. Magnetic fluid and an iron cylinder were immersed in Fluorinert. Two solenoids were alternately activated according to control signals from a computer. Two experiments were conducted: (1) magnetic fluids alone were used. (2) A combination of magnetic fluids and the iron cylinder was used. This combination was used as a substitute for magnetic fluids with high magnetization.With the use of magnetic fluids alone, a flow of 26 mL/min was obtained at 140 beats/min. Closing pressure was 13 mmHg. With the use of magnetic fluids and the iron cylinder, a flow of 318 mL/min was obtained at 260 beats/min. Closing pressure of 300 mmHg was obtained.With the use of magnetic fluids and the iron cylinder, 90 % flow of the maximum flow was obtained. Calculation disclosed that a driving pressure over 100 mmHg is obtained with the use of magnetic fluids with a magnetization of 113 kA/m.A magnetic fluid-driven artificial heart could be feasible if magnetic fluids with a magnetization of 113 kA/m are developed.

人们已经研究了多种植入式人工心脏。然而，它们具有利用轴承和复杂的驱动机构的共同缺点。另一方面，磁性流体致动器仅通过施加磁场直接驱动磁性流体，并且不需要轴承。为研究磁流体驱动人工心脏的可行性，在外径为10 mmOD，内径为7.4mmID的丙烯酸树脂管附近放置两个气隙为10 mm的环形电极。将小球囊（体积：2 mL）连接到丙烯酸管的两端。将球囊装入具有入口和出口的刚性盒中。丙烯酸管和球囊填充Fluorinert。将磁性流体和铁圆柱体浸入Fluorinert中。根据来自计算机的控制信号交替地激活两个触发器。进行了两个实验：（1）单独使用磁流体。(2)磁流体和铁圆筒的组合被使用。该组合用作具有高磁化强度的磁性流体的替代物。单独使用磁性流体时，在140次/min下获得26 mL/min的流量。关闭压力为13 mmHg。在260次/min的心跳下，使用磁性液体和铁筒，流量达到318 mL/min，关闭压力达到300 mmHg，流量达到最大流量的90%。计算表明，使用磁化强度为113 kA/m的磁流体可获得100 mmHg以上的驱动压力，研制出磁化强度为113 kA/m的磁流体可实现磁流体驱动的人工心脏。