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Development of an axial flow blood pump using a hydrodynamic pressure bearing

使用流体动压轴承的轴流血泵的开发

基本信息

批准号：
14380386
负责人：
MITAMURA Yoshinori
金额：
$ 10.69万
依托单位：
HOKKAIDO UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2002
资助国家：
日本
起止时间：
2002 至 2005
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14380386/
关键词：
Artificial heart Blood pump Hydrodynamic pressure bearing Magnetic fluid seal Computational fluid dynamics 磁気シール

项目摘要

An axial flow blood pump was developed using a hydrodynamic pressure bearing, a magnetic fluid seal and a brushless direct current motor. This enabled contact-free rotation of the impeller without material wear. The motor rotor is directly connected to the impeller by a motor shaft. A hydrodynamic pressure bearing is installed on the motor shaft. The motor and the hydrodynamic bearing are housed in a cylindrical casing and are waterproofed by a magnetic fluid seal. The magnetic fluid seal was developed for use in an axial-flow blood pump. Sealing pressures at motor speeds of up to 10,000 rpm were measured with the seal immersed in water. The sealing pressure was above 400 mm Hg. The seal, installed in the pump, remained perfect for 60 days at a flow of 4 L/min against a pressure of 150 mmHg. Results of measurement of cell growth activity indicated that the magnetic fluid has no negative cytological effects. The developed blood pump could eject a flow of 5 L/min at a pressure difference of 100 mmHg with an allowable hemolysis level (N.I.H.<0.02).The axial flow blood pump was implanted in goats between the left ventricle and the descending aorta. The goat survived for two days and a total left ventricular bypass was obtained with the pump.A control system of the axial flow blood pump was developed. A prediction method of the pump flow based on power consumption of the motor and motor speed was proposed. Pump flow was predicted with an error of less than 10%. Backflow through the pump and obstruction of the inflow cannula were automatically detected based on the wave distortion rate of the motor current. The distortion rate was computed using the Walsh functions.

研制了一种采用动压轴承、磁流体密封和无刷直流电机的轴流式血泵。这使得叶轮的无接触旋转没有材料磨损。电机转子通过电机轴直接连接到叶轮。在电机轴上装有动压轴承。电动机和流体动压轴承安装在一个圆柱形外壳内，并通过磁流体密封件进行防水。磁流体密封是为轴流式血泵研制的。在电机转速高达10，000 rpm的情况下，将密封件浸入水中，测量密封压力。密封压力高于400 mm Hg。安装在泵中的密封件在150 mmHg的压力下以4 L/min的流量保持完美60天。细胞生长活性的测定结果表明，磁流体没有负面的细胞学效应。所研制的血泵可在100 mmHg的压差下喷射5 L/min的流量，且允许溶血水平（N.I.H.）。将轴流式血泵植入山羊左心室与降主动脉之间。实验动物存活2 d后，用该泵实现了全左心室转流。提出了一种基于电机功耗和电机转速的泵流量预测方法。泵流量的预测误差小于10%。根据电机电流的波形失真率自动检测通过泵的回流和流入套管的阻塞。使用沃尔什函数计算失真率。