Multi-dimensional Spectral Analysis for Biomedical Parameters

生物医学参数的多维光谱分析

• 批准号: 11650038
• 负责人: ITOH Masahide
• 金额: $ 2.18万
• 依托单位: University of Tsukuba
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1999
• 资助国家: 日本
• 起止时间: 1999 至 2000
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11650038/
• 关键词: Spectral Analysis; biology; human skin; hemogrobine; meranine; seattering; spectroscopy; tattoo; 光散乱対; スペクトル計測; 相関法; 次元解析; モンテカルロ

We studied to extract spectral components for the identical behavior by taking the correlation between each wavelength of the parameter. In this method the preliminary processing is unnecessary. Though it is difficult that the features are judged by the human when the parameter is over two. It is possible to carry out the spectrum analysis of the complicated system which followed many parameters only by detecting the peak of the correlation in the multidimensional space.The light diffusion in the strong scatterer was simulated like the human skin. It was possible that the technique reported carried out Monte Carlo simulation to which also newly took in spectroscopic information. The skin was irradiated with the ultraviolet ray, and spectral data of the post-irradiation were acquired, and the change of melanin and hemoglobin was measured. The experiment in which the ultraviolet ray quantity changed was carried out, and the result was analyzed.The technique which estimated the visual performance after the injection from the pigmentary color before it injects the human skin to the hypodermic on gelatine model and collected actually was examined, and the clinical application was tried.

我们研究了利用参数各波长之间的相关性来提取相同行为的光谱成分。在这种方法中，不需要预先处理。尽管当参数大于2时，人类很难对特征进行判断。只有在多维空间中检测相关峰，才能对多参数复杂系统进行频谱分析。光在强散射体中的扩散模拟与人体皮肤相似。有可能所报道的技术进行了蒙特卡罗模拟，其中也新吸收了光谱信息。用紫外线照射皮肤，获取照射后的光谱数据，并测量黑色素和血红蛋白的变化。进行了紫外量变化实验，并对实验结果进行了分析。对实际采集的明胶模型人体皮肤皮下注射前从色素颜色预估注射后视觉性能的技术进行了检验，并进行了临床应用试验。

项目成果

M.Shimada, J.Hata, Y.Yamada, M.Itoh, A.Uchida, T.Yatagai: "Change in the color appearance for a pigment under the skin"Kogaku. 29. 392-398 (2000)

M.Shimada、J.Hata、Y.Yamada、M.Itoh、A.Uchida、T.Yatagai：“皮肤下色素颜色外观的变化”Kogaku。

H.Huang,M.Itoh and T.Yatagai: "Optical Scalable Parallel Modified Signed-digit Algorithms for Large-scale Array Addition and Multiplication Using Digital-decomposition-plane Representation"Optical Engineering. 38巻3号. 432-440 (1999)

H. Huang、M. Itoh 和 T. Yatagai：“使用数字分解平面表示的大规模阵列加法和乘法的光学可扩展并行改进的符号数字算法”，第 38 卷，第 3 期，432- 440（1999）

M.Shimada et.al.: "Ecplanation of the human skin color by multiple linear regression analysis based on the moditied Lanbery-Beer law"Opti Rev. 7. 348-352 (2000)

M.Shimada 等人：“基于修改后的兰伯里-比尔定律通过多元线性回归分析人类肤色的 Ecplanation”Opti Rev. 7. 348-352 (2000)

M.Shimada, Y.Masuda, Y.Yamada, M.Itoh, M.Takahashi and T.Yatagai: "Ecplanation of the human skin color by multiple linear regression analysis based on the modified Lambert-Beer law"Optical Review. 7. 348-352 (2000)

M.Shimada、Y.Masuda、Y.Yamada、M.Itoh、M.Takahashi 和 T.Yatagai：“基于修正朗伯-比尔定律的多元线性回归分析人类肤色的 Ecplanation”光学评论。

K.Harada,K.Munakata,Y.Yagai,M.Itoh,S.Umegaki,T.Yatagai: "Design of electrically addressed light modulators using one-dimensional photonic crystals with second-order nonlinearity"Nonlinear Optics. 24. 139-146 (2000)

K.Harada、K.Munakata、Y.Yagai、M.Itoh、S.Umegaki、T.Yatagai：“使用具有二阶非线性的一维光子晶体设计电寻址光调制器”非线性光学。