Biomimetic control on ceramics surfaces by polarization induction

通过极化感应对陶瓷表面进行仿生控制

• 批准号: 11650855
• 负责人: NAKAMURA Satoshi
• 金额: $ 1.92万
• 依托单位: Tokyo Medical and Dental University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1999
• 资助国家: 日本
• 起止时间: 1999 至 2000
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11650855/
• 关键词: hydroxyapatite; Apatite; Polarization; BIomimetic; Sol-gel method; Cell culture

The conformation of organic compound deposited on hydroxyapatite (HAp) ceramics was manipulated by their surface charge induced by electrical polarization. The sintered HAp ceramics were electrically polarized in a d.c. field at 4O0℃. The organic layers on the HAp ceramics were deposited from a toluene solution of phenyltrichlorosilane (PTCS). The results of contact angle measurements and IR spectroscopy clarified the organic layer containing the fragments of PTCS.The amount of the obtained layer on the positively charged surface was those on the negatively charged and non-polarized surfaces. The thickness of the layer on the non-polarized surfaces was thinner than those on the polarized surfaces, based on the depth profiles of Ca2p and Si2p. Although the deposition prepared on the non-polarized HAp surfaces from the PTCS solution was supposed to be a self-assembled layer including of phenyl-Si bond, the layers on the polarized HAp were aggregated irregularly. Consequently, the HAp ceramic surface charge induced by the polarization altered the electrostatic interaction to the organic compounds in non-aqueous system.

利用电极化诱导的表面电荷控制沉积在羟基磷灰石（HAp）陶瓷上的有机化合物的构象。烧结后的HAp陶瓷在400 ℃的直流电场中进行了极化。HAp陶瓷上的有机层是从苯基三氯硅烷（PTCS）的甲苯溶液中沉积的。接触角测量和红外光谱的结果澄清了含有PTCS碎片的有机层，在带正电的表面上得到的层的数量与在带负电和非极化表面上得到的层的数量相同。基于Ca 2 p和Si 2 p的深度分布，非极化表面上的层的厚度比极化表面上的层的厚度薄。虽然PTCS溶液在非极化HAp表面上形成的沉积物被认为是一个包含苯基-Si键的自组装层，但极化HAp上的层是不规则聚集的。因此，在非水体系中，HAp陶瓷表面的极化引起的电荷改变了与有机物的静电相互作用。

项目成果

S.Nakamura: "Modification of Assembled Structures of Steroids Adsorbed on Apatite Ceramic Surface by Electrical Poling"Mat.Res.Soc.Symp.Proc.. 599. 343-346 (2000)

S.Nakamura：“通过极化对磷灰石陶瓷表面吸附的类固醇的组装结构进行改性”Mat.Res.Soc.Symp.Proc.. 599. 343-346 (2000)

M.Ohgaki: "Vectorial Effects on Selective cell Adhesion of Electrically poled Hydroxyapatite ceramics"Bioceramics. 12. 187-190 (1999)

M.Ohgaki：“矢量对极化羟基磷灰石陶瓷选择性细胞粘附的影响”生物陶瓷。

S.Nakamura: "Proton Transport Polarization and Deporaization of Hydroxyapatite Ceramics"J.Appl.Phys.. (印刷中). (2001)

S. Nakamura：“羟基磷灰石陶瓷的质子传输极化和脱孔”J. Appl.（出版中）。

S.Nakamura: "Formation of Nonstoichiometric Hydroxyapatite Microcrystals in High pH Region"Phos.Res.Bull.. 11. 1-6 (2000)

S.Nakamura：“高 pH 区域中非化学计量羟基磷灰石微晶的形成”Phos.Res.Bull.. 11. 1-6 (2000)

T.Ikoma: "Preparation and Dielectric Property of Sintered Monoclinic Hydroxyapatite"J.Meter.Sci.Lett.. 18. 1225-1228 (1999)

T.Ikoma：“烧结单斜羟基磷灰石的制备和介电性能”J.Meter.Sci.Lett.. 18. 1225-1228 (1999)