BIOORGANIC STUDIES ON BIOFUNCTIONAL COMPONENTS IN VEGETABLES FOR CHEMICAL BREEDING

化学育种蔬菜中生物功能成分的生物有机研究

基本信息

批准号：
11660113
负责人：
FUKUI Hiroshi
金额：
$ 2.43万
依托单位：
Kagawa University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1999
资助国家：
日本
起止时间：
1999 至 2001
项目状态：
已结题

项目摘要

These epidemiological predictions suggest that vegetables and fruits contain anticancer or antitumor-promoting components. Thus the physiologically functional components in vegetables could be good sources of chemopreventive agents with low-toxicity available in our daily food supply. In this research project, antitumor promoting and antioxidating components were searched in spinach, burdock, moroheiya and broccoli. The results were shown below.1. Two kinds of monogalactosyldiacylgricerols having unsaturated fatty acids were isolated and identified as antitumor promoting components. The activity was almost the same with active components isolated from medicinal plants. In addition, the contents significantly varied among the cultivars and with culture conditions.2. Three chlorogenic acid derivatives known as antioxidating activity were identified in burdock. The contents also varied among the cultivars.3. Young jute (moroheiya) leaves were found to contain monogalactosyldiacylgricerols having unsaturated fatty acids and a diterpene, phytol, as antitumor promoting components. The contents increased after treatment with hot water, suggesting that these active components did not decompose during cocking.4. Two monoacylglycerides were isolated from flower buds of broccoli as antitumor promoters. These components could be interestingly derived from monogalactosyldiacylgricerols during catabolism in human body.These results indicate that vegetables contain many biofunctional components useful for keeping health well and that the contents of functional components significantly vary among the cultivars.

这些流行病学预测表明蔬菜和水果含有抗癌或抗肿瘤成分。因此，蔬菜中的生理功能成分可能是我们日常食品供应中具有低毒性的化学预防剂的良好来源。在该研究项目中，在菠菜，牛burdock，Moroheiya和西兰花中搜索了抗肿瘤促进和抗氧化成分。结果如下所示。1。分离并鉴定为抗肿瘤促进成分的两种类型的单乳乳糖基糖果醇。从药用植物中分离出的活性成分几乎相同。另外，含量在品种和培养条件下都有很大不同。2。在牛群中鉴定出三种称为抗氧化活性的氯化酸衍生物。含量在品种之间也有所不同。3。发现年轻的黄麻（Moroheiya）叶子包含具有不饱和脂肪酸的单乳糖基二糖基果酚，而二甲二烯（二萜）作为抗肿瘤促进成分。用热水处理后的含量增加，表明这些活性成分在翘起期间没有分解。4。从西兰花的花蕾中分离出两种单酰基甘油三酸酯作为抗肿瘤启动子。这些成分可能是从人体分解代谢期间源自单摩乳乳糖基质基果醇的有趣的。这些结果表明，蔬菜包含许多可用于保持健康状况良好的生物功能成分，并且在品种中的功能成分的含量明显变化。