Analyses of mechanism of pain through use of blood flow status evaluated by a color Doppler sonography in masticatory muscles

通过彩色多普勒超声检查咀嚼肌血流状态分析疼痛机制

• 批准号: 12671842
• 负责人: ARIJI Eiichiro
• 金额: $ 2.11万
• 依托单位: Aichi Gakuin University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2000
• 资助国家: 日本
• 起止时间: 2000 至 2001
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12671842/
• 关键词: Massete rmuscle; Color Doppler sonography; Blood flow; Pain; Fatigue; Contraction; Facial Artery; 咀嚼筋; 超音波断層法; 疼痛

The vascular appearances were examined for the four main arteries feeding the masseter muscle in healthy volunteers (n=38). The features of these arteries were investigated together with the flow diameter, flow velocities and arterial resistances. The symmetry indices were also calculated to assess their pathological changes. The detection rates of the branch from the transverse facial artery, the masseter artery and the branch from the maxillary or external carotid artery were 98.7 %, 21.1 % and 84.2 % in healthy volunteers, respectively. The facial artery feeding the muscle from the inferior part represented two patterns according to anatomical variant, that is, the masseteric branch (22.4 %) and the main trunk itself (77.6 %). The means of the flow diameter, maximum and minimum velocities, resistive index (RI) and pulsatility index (PI) in healthy subjects were 1.8 mm, 24.6 cm/sec, 5.1 cm/sec, 0.80 and 2.51, respectively.Muscle edema, which can be evaluated as a thickness increment by ultrasonography, plays an important role in provoking pain and fatigue in low-level contraction. Although edema is related to the balance of in- and out-flows of blood, there are no data regarding the relationship between thickness change and blood flow. The blood flow velocities of the facial artery were measured by color Doppler ultrasonography in 30 healthy volunteers during 20 minutes contraction with 10 % of maximum force together with thickness change. Both the thickness and flow velocity changes reached a peak in the initial phase of contraction. The initial change of thickness did not correlate to the velocities of the facial artery, while those immediately after exercise showed a high correlation. The velocity changes of the facial artery might depend on both the general response to the contraction and the local metabolic or mechanical factors in the contracted masseter muscles.

对38例健康志愿者的咬肌四条主要动脉的血管形态进行了观察。并结合血流内径、血流速度、动脉阻力等指标对这些动脉的形态特征进行了研究。计算对称性指数，评价其病理变化。健康志愿者面横动脉分支、咬肌动脉分支和上颌或颈外动脉分支的检出率分别为98.7%、21.1%和84.2%。下部供血的面动脉按解剖变异分为咬肌支(22.4%)和主干本身(77.6%)两种类型。正常人的平均血流内径为1.8 mm，最大流速为24.6 cm/s，最小流速为5.1 cm/s，阻力指数(RI)为0.80，搏动指数(PI)为2.51。虽然水肿与血液流入和流出的平衡有关，但没有关于厚度变化和血流量之间的关系的数据。用彩色多普勒超声测定了30名健康志愿者面部动脉在10%最大压力收缩20min时的血流速度，并分析了其厚度的变化。厚度和流速变化均在收缩初期达到峰值。最初的厚度变化与面动脉的血流速度没有相关性，而运动后即刻的厚度变化与面动脉的速度有很高的相关性。面动脉的血流速度变化可能既取决于对收缩的一般反应，也取决于收缩的咬肌局部代谢或机械因素。

项目成果

有地 榮一郎, 有地 淑子, 佐久間 重光, 木村 泰男: "超音波ドップラ法による血流の描出:顎顔面領域への応用"歯科放射線. 41・1. 3-12 (2001)

有地荣一郎、有地芳子、佐久间重光、木村康夫：“利用超声波多普勒法的血流图解：在颌面部的应用”《牙科放射学》41・1（2001）。

Ariji Y, Sakuma S, Kimura Y, Kawamata A, Toyama M, Kurita K, Itoh Y, Ariji E.: "Colour Doppler sonographic analysis of blood-flow velocity in the human facial artery and changes in masseter muscle thickness during low-level static contraction"Arch Oral Bi

Ariji Y、Sakuma S、Kimura Y、Kawamata A、Toyama M、Kurita K、Itoh Y、Ariji E.：“彩色多普勒超声分析人类面部动脉血流速度和低水平咬肌厚度变化

Ariji E, Ariji Y, Sakuma S. Zhao YP.: "Color Doppler sonography of the facial artery"Oral Radiology. 17・1. 10-14 (2001)

Ariji E，Ariji Y，Sakuma S.Zhao YP.：“面部动脉的彩色多普勒超声检查”口腔放射学17・1（2001）。

有地栄一郎, 有地淑子, 佐久間重光, 木村泰男: "超音波ドップラ法による血流の描出:顎顔面領域への応用"歯科放射線. 41・1. 3-12 (2001)

有地英一郎、有地芳子、佐久间重光、木村康夫：“利用超声波多普勒法的血流图解：在颌面部的应用”《牙科放射学》41・1（2001）。

Ariji Y, Kimura Y, Gotoh M, Sakuma S, Zhao YP, Ariji E.: "Blood flow in and around the masseter muscle Normal and pathology features demonstrated by color Doppler sonography"Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 91・4. 472-482 (2001)

Ariji Y、Kimura Y、Gotoh M、Sakuma S、Zhao YP、Ariji E.：“彩色多普勒超声检查显示咬肌内部和周围的血流正常和病理特征”Oral Surg Oral Med Oral Pathol Oral Radiol Endod 91・4. 472-482 (2001)