Explication of masticatory muscle pain mechanisms in hemodynamics and establishment quantitative evaluation of treatment method.

研究了咬肌的基本血流动力学，以阐明咬肌疼痛和疲劳的原因。本研究的第一个目的是确认近红外光谱（NIRS）在人类咬肌中的应用。使用近红外光谱检查咬肌的血流动力学，包括传感器定位点、昼夜节律、超昼夜节律、代际性别差异和最大自觉握紧。同时对伴有肌筋膜疼痛的女性颞下颌紊乱（TMD）患者的超声表现进行了研究，并与健康志愿者进行了比较。超声表现明确，可能与肌肉水肿有关。此外，经皮神经电刺激（TENS）后，用近红外光谱（NIRS）检查血流动力学的变化。在临床病例中，我们验证了稳定夹板对TMD患者的疗效。CT检查冠突增生。总之，超声和近红外光谱似乎是一个有前途的工具，评估肌肉患者TMD。

The basic hemodynamics of masseter muscle was investigated to clarify the cause of pain and fatigue of masseter muscle. The first purpose of this investigation is to confirm the application of near infrared spectroscopy (NIRS) in the human masseter muscle. Hemodynamics of masseter muscle is examined regarding the point of sensor positioning, circadian, ultradian rhythms, intergeneration sex difference and maximum voluntary clenching using NIRS. Simultaneously ultrasonographic appearances were studied in female patients with temporomandibular disorder (TMD) associated with myofascial pain in comparison with healthy volunteers. The ultrasonographic features were clarified and they might be related to muscle edema. Furthermore, changes of hemodynamics were examined with a NIRS after transcutaneous electrical nerve stimulation (TENS). In clinical cases, we verified efficacy of stabilization splint for patients with TMD. Coronoid process hyperplasia were also investigated with CT. In conclusion, the ultrasonography and NIRS appeared to be a promising tool for evaluation of the muscle in patients with TMD.