Soft Matter Complex Systems as Model Biological Systems

软物质复杂系统作为生物系统模型

• 批准号: 15340138
• 负责人: IMAI Masayuki
• 金额: $ 10.24万
• 依托单位: Ochanomizu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2003
• 资助国家: 日本
• 起止时间: 2003 至 2005
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15340138/
• 关键词: Soft Matter Complex System; Macromolecules; Liquid Crystal; Surfactant; Depletion Interaction; Model Biomembrane; 生体モデル; 両親媒性分子; ラフトモデル; 発芽現象; 棒状コロイド粒子; リン脂質膜; 秩序メソ構造; マイクロドメイン; オニオン構造; 両親媒性分子膜; 棒状粒子; 両親媒性高分子; 膜間相互作用; 曲げ弾性率

In this project, we investigated the structure formation of Soft Matter Complex Systems as Model Biological Systems. Especially we focused on the following three complex systems, which may have relation to the biological functionalities.1)Liquid crystal + polymer complex system :Biopolymers having anisotropic shapes, such as protein, virus and actin-filament, forms characteristic aggregates in the biological circumstance. The basic attractive interaction between the anisotropic particles may be originated from the so-called depletion interaction. In this study we found that the rigid polymer enhances the depletion interaction about 1000 times compared with the case of coil-like polymer chains. This is due to the large effective excluded volume of the rigid polymer chains.2)Surfactant membrane + polymer chain (colloidal particle) system :We have investigated effects of a guest component (polymer or spherical colloidal particle) confined between flexible lamellar slits on the inter-lamel … More lar interaction. The addition of the neutral polymer into the lamellar phase induces an attractive inter-lamellar interaction. On the other hand, the spherical colloidal particles confined between the flexible lamellar membranes reduce the undulational fluctuations of lamellae and bring a repulsive inter-lamellar interaction.3)Polymer grafted surfactant membranesWe have investigated the effects of grafted polymer chains on the bending modulus and the inter-membrane interactions of lamellar membranes. The bending modulus of the polymer grafted membranes increases in proportion to the square of the end to end distance of the polymer chain. The mushroom layer is renormalized to the membrane thickness, which enhances the repulsive Helfrich interaction. When the size of the decorated polymer chain increases to the inter-lamellar distance, however, the mushroom is squeezed so as to optimize the inter-lamellar potential. Further increase of the grafted polymer size brings a lamellar-lamellar phase separation. Less

在本项目中，我们研究了作为模型生物系统的软物质复杂系统的结构形成。其中，重点研究了与生物功能相关的三种复杂体系：1）液晶+高分子复合体系：具有各向异性形状的生物高分子，如蛋白质、病毒、肌动蛋白丝等，在生物环境中形成特征性聚集体。各向异性粒子之间的基本吸引相互作用可能起源于所谓的耗尽相互作用。在这项研究中，我们发现，刚性聚合物增强耗尽相互作用约1000倍的情况下相比，线圈状聚合物链。2）表面活性剂膜+聚合物链（胶体颗粒）系统：我们研究了客体组分（聚合物或球形胶体颗粒）被限制在柔性片层狭缝之间对层间结构的影响。 ...更多信息 最大交互作用。将中性聚合物添加到层状相中诱导了有吸引力的层间相互作用。另一方面，球形胶体粒子被限制在柔性层状膜之间，降低了层状膜的起伏波动，并带来了排斥性的层间相互作用。3）聚合物接枝表面活性剂膜我们研究了接枝聚合物链对层状膜的弯曲模量和膜间相互作用的影响。聚合物接枝膜的弯曲模量与聚合物链的端到端距离的平方成比例地增加。蘑菇层被重整化为膜厚度，这增强了排斥的Helfrich相互作用。然而，当修饰的聚合物链的尺寸增加到层间距离时，蘑菇被挤压以优化层间电势。接枝聚合物尺寸的进一步增加导致层片-层片相分离。少

项目成果

Polymer-Confinement-Induced Nematic Transition of Microemulsion Droplets

聚合物约束诱导的微乳液液滴向列相转变

• 发表时间: 2005
• 期刊: Europhys.Lett. 71
• 作者: K.Nakaya;M.Imai;S.Komura;T.Kawakatsu;N.Urakami
• 通讯作者: N.Urakami

Inter-lamellar interactions modulated by addition of guest components

通过添加客体成分调节层间相互作用

• 发表时间: 2004
• 期刊: Eur.Phys.J.E. 20
• 作者: M.Imai;R.Mawatari;K.Nakaya;S.Komura
• 通讯作者: S.Komura

Anomalous Decrease in Lamellar Spacing by Shear Flow in a Nonionic Surfactant/Water System

非离子表面活性剂/水体系中剪切流引起的层间距异常减小

• 发表时间: 2004
• 期刊: Langmuir 20
• 作者: T.Kato;et al.
• 通讯作者: et al.

Polymer Crystallization from the Metstable Melt ; The formation mechanism of spherulites

聚合物从 Metstable 熔体中结晶；

• 期刊: Polymer, (in press)
• 作者: T.Masui;et al.;M.Imai et al.
• 通讯作者: M.Imai et al.

Shear-Induced Structural Transition in a Lyotropic Lamellar Phase Studied by Small-Angle Neutron and Light Scattering

通过小角中子和光散射研究溶致层状相中剪切引起的结构转变

• 发表时间: 2005
• 期刊: J.Phys. : Condens.Matter 17
• 作者: T.Kato;K.Miyazaki;Y.Kawabata;S.Komura;M.Fujii;M.Imai
• 通讯作者: M.Imai