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Relationships between the activities of color selective neurons in the inferior temporal cortex of the monkey and color discrimination behavior

猴颞下皮层颜色选择神经元活动与颜色辨别行为的关系

基本信息

批准号：
16300103
负责人：
KOMATSU Hidehiko
金额：
$ 9.15万
依托单位：
National Institute for Physiological Sciences
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2004
资助国家：
日本
起止时间：
2004 至 2006
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16300103/
关键词：
Vision Perception Color vision Discrimination Judgement Macaque monkey Neuron activity Inferior temporal cortex カテゴリー

项目摘要

On the basis of lesion or electrophysiological studies, it is suggested that area TE (anterior part of IT), which is the highest area in the ventral stream of visual information processing, plays an important role for information processing of color.To study whether there exists dose link between color selective responses of TE neurons and perception, we examined the correlation between monkey's color judgment and responses of color selective TE neurons. We trained a fine color discrimination task in two monkeys and recorded single neuron activities from the color-sensitive sub-region in area TE. In this task, a sample color stimulus was presented at the confer of the display, and the monkey had to make either the rightward or leftward saccade depending on the similarity of the sample color to the two target colors. Two target colors were determined based on the color selectivity of each neuron such that one target color (preferred target color) evoked stronger response than the other … More color (non-preferred target odor). Sample color in each trial was chosen from seven colors equally spaced between the target colors on the CIE-xy chromaticity diagram. First, we quantitatively compared the color discrimination abilities of neurons and the monkeys. To calculate the discrimination ability of the neuron, we computed neurometric function by ROC analysis based on the assumption that neural responses to the center color of sample color set are used as the reference for the color judgment. We then compared neural threshold based on the neurometric function and behavioral threshold based on the psychometric function as the color separation which yielded 80% correct color judgments. We found that in general neural threshold was lower than the behavioral threshold although in some neurons both are comparable. Variation of the neural threshold across the color space corresponded well with that of behavioral threshold. We then calculated the Choice Probability (CP) that is a quantitative measure of correlation between trial-to-trial fluctuation of neural responses and the monkey's color judgment. We found that CP are on average larger than 0.5 and this is consistent with the expectation that the activities of these TE neurons positively correlate with the monkey's color judgment. Finally, we found that there is little correlation between the neural threshold for color discrimination and CP. This suggests that a large population of color selective TE neurons having various color sensitivity rather than a specific subset of neurons with particularly high color sensitivity contribute to the color discrimination performance. Less

根据损伤或电生理研究，建议TE区TE神经元是视觉信息处理的腹侧流的最高区，在颜色信息处理中起着重要作用，为了研究TE神经元的颜色选择反应与知觉之间是否存在剂量联系，我们研究了猴子的颜色判断和颜色选择TE神经元反应之间的相关性。我们在两只猴子身上训练了一个精细的颜色辨别任务，并记录了TE区颜色敏感子区域的单个神经元活动。在这项任务中，在显示器的赋予处呈现样品颜色刺激，并且猴子必须根据样品颜色与两种目标颜色的相似性进行快速扫视或快速扫视。基于每个神经元的颜色选择性确定两种目标颜色，使得一种目标颜色（优选目标颜色）比另一种引起更强的响应 ...更多信息颜色（非首选目标气味）。每个试验中的样品颜色选自CIE-xy色度图上目标颜色之间等距的七种颜色。首先，我们定量比较了神经元和猴子的颜色辨别能力。为了计算神经元的辨别能力，我们通过ROC分析来计算神经度量函数，该ROC分析基于神经对样本颜色集合的中心颜色的响应被用作颜色判断的参考的假设。然后，我们比较了基于神经功能的神经阈值和基于心理功能的行为阈值作为颜色分离，产生了80%的正确颜色判断。我们发现，一般来说，神经阈值低于行为阈值，虽然在某些神经元两者是可比的。神经阈值在颜色空间的变化与行为阈值的变化相对应。然后，我们计算了选择概率（CP），这是一个定量测量之间的相关性试验到试验波动的神经反应和猴子的颜色判断。我们发现，CP平均大于0.5，这是一致的预期，这些TE神经元的活动与猴子的颜色判断呈正相关。最后，我们发现，有很少的相关性之间的神经阈值的颜色辨别和CP。这表明具有各种颜色敏感性的大量颜色选择性TE神经元而不是具有特别高的颜色敏感性的特定神经元子集有助于颜色辨别性能。少