Rosetting of infected erythrocyte and virulence of Vivax malaria
Rosetting of infected erythrocyte and virulence of Vivax malaria
批准号:
18406009
负责人:
TORII Motomi
金额:
$10.14万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2006
资助国家:
日本
项目状态:
已结题
起止时间:
2006 至 2008
中文摘要
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英文摘要
ヒトに感染する三日熱マラリア原虫の感染赤血球が非感染赤血球に接着する現象(ロゼット形成)の起因となる原虫分子を明らかにし、病原性との関連を解析する研究である。マラリア流行地にてロゼット形成試験を行い、それと関連する原虫接着分子候補を検討したが、明らかなものは見られなかった。一方、マラリア患者体内には接着分子候補の一つに対する抗体があること、また、この分子にはヒト免疫によると思われる正の淘汰圧がかかっていることを明らかにできた。
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Characterization of Plasmodium vivax subtelomeric transmembrane protein (PvSTP), ahomolog of P. falciparum SURFIN
间日疟原虫亚端粒跨膜蛋白 (PvSTP)(恶性疟原虫 SURFIN 的同源物)的表征
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Sungkapong T, Culleton R, Yahata K, Tsuboi T, Torii M. Sattabongkot J. Kaneko O, Chotivanch K]
通讯作者:
Chotivanch K
Characterization of Plasmodium vivax subtelomeric transmembrane protein(PvSTP), a homolog of P. falciparum SURFIN
间日疟原虫亚端粒跨膜蛋白 (PvSTP)(恶性疟原虫 SURFIN 的同源物)的表征
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Sungkapong T, Culleton R, Yahata K, Tsuboi T, Torii M, Sattabongkot J, Kaneko O, Chotivanch K]
通讯作者:
Chotivanch K
Development of novel transmission blocking vaccine targeting microgamete surface antigen of Plasmodium falciparum
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批准号:20H03480
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.32万
-
财政年份:2020
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负责人:TORII Motomi
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依托单位:
Assessment of P. vivax transmission-blocking activity of novel vaccine candidate (PvGs24)
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批准号:16H05816
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.32万
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财政年份:2016
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负责人:TORII Motomi
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依托单位:
Development of novel P. falciparum malaria transmission-blocking vaccine targeted against Pf75
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批准号:15H04725
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.98万
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财政年份:2015
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负责人:TORII Motomi
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依托单位:
Development of novel malaria transmission blocking vaccine
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批准号:21406010
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.23万
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财政年份:2009
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负责人:TORII Motomi
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依托单位:
Screening of sporozoite receptor molecule(s) on hepatocytes
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批准号:21390124
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.81万
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财政年份:2009
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负责人:TORII Motomi
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依托单位:
Identification of erythrocyte proteins interacting with RhopH complex of malaria parasites
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批准号:19390120
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.15万
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财政年份:2007
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负责人:TORII Motomi
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依托单位:
Identification of the binding domain of Plasmodium falciparum erythrocyte binding protein.
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批准号:16390126
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.66万
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财政年份:2004
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负责人:TORII Motomi
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依托单位:
Identification of the erythrocyte receptor for Plasmodium yoelii RhopH complex
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批准号:16017272
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$9.6万
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财政年份:2004
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负责人:TORII Motomi
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依托单位:
Analysis of the protein expression level of the erythrocyte binding proteins in Plasmodium falciparum field isolates.
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批准号:15406015
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.58万
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财政年份:2003
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负责人:TORII Motomi
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依托单位:
Structure and functional analysis of high molecule weight rhoptry protein complex, RhopH, of rodent malaria parasite.
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批准号:14370084
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.96万
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财政年份:2002
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负责人:TORII Motomi
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依托单位:
Expression of erythrocyte binding protein in Plasmodium falciparum merozoites isolated from endemic area
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批准号:13576007
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.7万
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财政年份:2001
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负责人:TORII Motomi
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依托单位:
Analyisis of the Plasmodial rhoptry protein function by gene targeting
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批准号:12670232
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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财政年份:2000
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负责人:TORII Motomi
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依托单位:
Role of the rhoptry proteins of sporozoites during hepatocyte invasion by Plasmodium
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批准号:09670262
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.73万
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财政年份:1997
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负责人:TORII Motomi
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依托单位:
Efficacy of the monoclonal antibodies and their mechanism of transmission-blocking activitiesof Plasmodium yoelii in Anopheles stephensi.
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批准号:07670279
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.34万
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财政年份:1995
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负责人:TORII Motomi
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依托单位:
PROTEINS LOCALIZED IN THE APICAL ORGANELLES IN OOKINETES OF THE MALARIA PARASITE.
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批准号:05807020
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.02万
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财政年份:1993
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负责人:TORII Motomi
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依托单位:
海外基金