Identification of erythrocyte proteins interacting with RhopH complex of malaria parasites
Identification of erythrocyte proteins interacting with RhopH complex of malaria parasites
批准号:
19390120
负责人:
TORII Motomi
金额:
$12.15万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
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英文摘要
マラリア原虫メロゾイトは、宿主赤血球侵入時に先端部小器官からタンパク質を分泌する。先端部小器官から分泌されるタンパク質の中で、ロプトリーから分泌される高分子ロプトリータンパク質複合体(RhopH複合体)の赤血球侵入における役割は分かっていない。本研究では、RhopHの赤血球侵入時における機能の解明に向けて、RhopH複合体と相互作用する赤血球タンパク質の検索を行った結果、RhopH複合体と結合するタンパク質を見いだすことに成功した。
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
A ccmplex formation of rhoptry neck protein 2 with a microneme protein, AMA1, in Plasmodium falciparum.
恶性疟原虫中棒状体颈蛋白 2 与微线体蛋白 AMA1 的复合体形成。
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[曹俊, 金子修, Thongkukiatkul Amporn, 橘真由美, 大槻均, 坪井敬文, 鳥居本美]
通讯作者:
鳥居本美
DOI:
10.1016/j.parint.2006.11.001
发表时间:
2007-03-01
期刊:
PARASITOLOGY INTERNATIONAL
影响因子:
1.9
作者:
[Ghoneim, Ahmed, Kaneko, Osamu, Torii, Motomi]
通讯作者:
Torii, Motomi
Development of novel transmission blocking vaccine targeting microgamete surface antigen of Plasmodium falciparum
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批准号:20H03480
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.32万
-
财政年份:2020
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负责人:TORII Motomi
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依托单位:
Assessment of P. vivax transmission-blocking activity of novel vaccine candidate (PvGs24)
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批准号:16H05816
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.32万
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财政年份:2016
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负责人:TORII Motomi
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依托单位:
Development of novel P. falciparum malaria transmission-blocking vaccine targeted against Pf75
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批准号:15H04725
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.98万
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财政年份:2015
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负责人:TORII Motomi
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依托单位:
Development of novel malaria transmission blocking vaccine
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批准号:21406010
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.23万
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财政年份:2009
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负责人:TORII Motomi
-
依托单位:
Screening of sporozoite receptor molecule(s) on hepatocytes
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批准号:21390124
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.81万
-
财政年份:2009
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负责人:TORII Motomi
-
依托单位:
Rosetting of infected erythrocyte and virulence of Vivax malaria
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批准号:18406009
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.14万
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财政年份:2006
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负责人:TORII Motomi
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依托单位:
Identification of the binding domain of Plasmodium falciparum erythrocyte binding protein.
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批准号:16390126
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.66万
-
财政年份:2004
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负责人:TORII Motomi
-
依托单位:
Identification of the erythrocyte receptor for Plasmodium yoelii RhopH complex
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批准号:16017272
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$9.6万
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财政年份:2004
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负责人:TORII Motomi
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依托单位:
Analysis of the protein expression level of the erythrocyte binding proteins in Plasmodium falciparum field isolates.
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批准号:15406015
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.58万
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财政年份:2003
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负责人:TORII Motomi
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依托单位:
Structure and functional analysis of high molecule weight rhoptry protein complex, RhopH, of rodent malaria parasite.
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批准号:14370084
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.96万
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财政年份:2002
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负责人:TORII Motomi
-
依托单位:
Expression of erythrocyte binding protein in Plasmodium falciparum merozoites isolated from endemic area
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批准号:13576007
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.7万
-
财政年份:2001
-
负责人:TORII Motomi
-
依托单位:
Analyisis of the Plasmodial rhoptry protein function by gene targeting
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批准号:12670232
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
-
财政年份:2000
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负责人:TORII Motomi
-
依托单位:
Role of the rhoptry proteins of sporozoites during hepatocyte invasion by Plasmodium
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批准号:09670262
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.73万
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财政年份:1997
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负责人:TORII Motomi
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依托单位:
Efficacy of the monoclonal antibodies and their mechanism of transmission-blocking activitiesof Plasmodium yoelii in Anopheles stephensi.
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批准号:07670279
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.34万
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财政年份:1995
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负责人:TORII Motomi
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依托单位:
PROTEINS LOCALIZED IN THE APICAL ORGANELLES IN OOKINETES OF THE MALARIA PARASITE.
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批准号:05807020
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.02万
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财政年份:1993
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负责人:TORII Motomi
-
依托单位:
海外基金