Molecular analysis of the regulation mechanism of systemic necrosis development in Arabidopsis thaliana upon bromovirus infection

病毒感染植物并引起各种症状。本研究分析了溴病毒感染对拟南芥系统性坏死发生的调控机制。突变体植物的遗传作图和互补试验表明，两个相邻的“抗性基因”是症状发展和功能合作的重要决定因素。突变分析表明，在这种病毒-植物系统中，系统性坏死的发展是一种伴随过敏反应样细胞死亡的弱而延迟的抗性反应形式。

Viruses infect plants and cause various types of symptoms. In this study, we analyzed the regulation mechanism of systemic necrosis development in Arabidopsis thaliana upon bromovirus infection. Genetic mapping and complementation tests in mutant plants revealed that two adjacent "resistance genes" are essential determinants for symptom development and function cooperatively. Mutational analyses suggest that systemic necrosis development in this virus-plant system is a form of weak and delayed resistance response accompanying hypersensitive reaction-like cell death.