Development of efficient drug analysis system in forensic practice

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A novel screening procedure using calibration locking databases was developed by GC/MS. The method does not require standard substances and semi-quantitative data can be obtained simultaneously. We also developed a rapid and quantitative screening method for 43 hypnotics by LC/MS. The attempt for developing the most efficient drug analysis system in Japan was made based on a retrospective study on the kinds of compounds causing poisonings and on the analysis of the frequency of their use employing two series of reports dealing with fatal poisoning cases and a review of the drug analysis system accompanied by forensic autopsy in Finland.