Effect of exercise to the lipid peroxide production and its detoxification excretion in human ingested docosahexaenoic acid

运动对人体摄入二十二碳六烯酸中脂质过氧化物产生及其解毒排泄的影响

• 批准号: 19500623
• 负责人: KUBO Kazuhiro
• 金额: $ 2.83万
• 依托单位: Nara Bunka Women's College
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19500623/
• 关键词: 生活習慣病; 運動・食事; ドコサヘキサエン酸; 過酸化脂質; 解毒・排出

Ingestion of docosahexaenoic acid (DHA) contained in a fish is effective for lifestyle-related disease prevention. However, it is known that DHA intake increases the lipid peroxides thought to be a cause of lifestyle-related disease. On the other hand, it has been reported that although high strength exercise increases lipid peroxides in tissues, moderate strength exercise enhances the antioxidative mechanisms in tissues conversely. This study examined relationship of DHA intake and exercise which is bases of lifestyle-related disease prevention. As results, it was suggested that habitual exercise and moderate strength exercise suppressed the lipid peroxides generated with DHA intake.

摄取鱼中所含的二十二碳六烯酸(DHA)对于预防与生活方式有关的疾病是有效的。然而，众所周知，DHA的摄入会增加被认为是与生活方式有关的疾病的原因之一的过氧化脂质。另一方面，有报道称，尽管高强度运动会增加组织中的过氧化脂质，但中等强度运动会反过来增强组织中的抗氧化机制。本研究探讨了DHA摄入量与运动的关系，这是生活方式相关疾病预防的基础。结果提示，习惯性运动和中等强度运动可抑制DHA摄入所产生的过氧化脂质。

项目成果

DHAの水銀排出作用に関するケーススタディー

DHA消汞效果案例研究

• 发表时间: 2008
• 期刊: 奈良文化女子短期大学紀要 第39号
• 作者: 久保和弘;馬場貴司;熊井司;蓮池豊子;斎藤衛郎
• 通讯作者: 斎藤衛郎