Gene Amplification of MYC and its coamplification with genes coding receptor tyrosine kinase in solid carcinomas
Gene Amplification of MYC and its coamplification with genes coding receptor tyrosine kinase in solid carcinomas
批准号:
19590342
负责人:
OOI Akishi
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2008
中文摘要
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英文摘要
胆嚢癌および乳癌について、DNA転写物質をコードするMYC, 容体型チロシンキナーゼをコードするERBB2, EGFR の遺伝子の増幅をfluorescence in situ hybridizationを用いて検索した。胆嚢癌では97 例中3例にMYCの増幅があり、1例でERBB2とEGFR、1例でERBB2の同時増幅を認めた。乳癌では91例中31例にMYCの増幅がみられ、このうち10例にERBB2の同時増幅をみとめた。
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Gene amplification of Myc and its coamplification with ERBB2 and EGFR in gallbladder adenocarcinoma.
DOI:
--
发表时间:
2009
期刊:
Anticancer research
影响因子:
2
作者:
[A. Ooi;Shioto Suzuki;K. Nakazawa;J. Itakura;I. Imoto;Hiroyuki Nakamura;Y. Dobashi]
通讯作者:
A. Ooi;Shioto Suzuki;K. Nakazawa;J. Itakura;I. Imoto;Hiroyuki Nakamura;Y. Dobashi
Critical and diverse involvement of the Akt/mTOR signaling in human lung carcinomas.
Akt/mTOR 信号传导在人类肺癌中的关键和多样化参与。
DOI:
--
发表时间:
2009
期刊:
Cancer 115(1)
影响因子:
--
作者:
[Dobashi, Y., Suzuki, S., Matsubara, H., Kimura, M., Endo, S., Ooi, A.]
通讯作者:
A.
Gene amplification of Myc and its coamplification with ERBB2 and EGFR in gallbladder adenocarcinomas.
胆囊腺癌中 Myc 的基因扩增及其与 ERBB2 和 EGFR 的共扩增。
DOI:
--
发表时间:
2009
期刊:
Anticancer Res. 29(1)
影响因子:
--
作者:
[Ooi, A., Suzuki, S., Nakazawa, K., Itakura, J., Imoto, I., Nakamura, H., Dobashi, Y.]
通讯作者:
Y.
A comprehensive study of HER2 aberration of gastric cancers in viewing as the target of molecular therapy
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批准号:22590310
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
-
财政年份:2010
-
负责人:OOI Akishi
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依托单位:
Analysis of the c-rtbB-2 and EGFR, and the ir downstream signal transduction system.
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批准号:17590298
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.37万
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财政年份:2005
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负责人:OOI Akishi
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依托单位:
Analysis of the receptor tyrosine kinase genes in the human solid cancers and its clinical application
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批准号:15590298
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2003
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负责人:OOI Akishi
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依托单位:
Protein overexpression and gene atplificntion of c-ertB-2(HER-2/neu) in human cancers
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批准号:12670157
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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财政年份:2000
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负责人:OOI Akishi
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依托单位:
Analysis of the numerical aberration of chromosome 17 and 18 on frozen section of gastric adenocarcinomas
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批准号:07670196
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.47万
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财政年份:1995
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负责人:OOI Akishi
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依托单位:
Numerical changes of chromosome 17p (p53locus) detected by FISH in gastric cancer
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批准号:05670170
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1993
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负责人:OOI Akishi
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依托单位:
海外基金