Analysis of secretion system of virulence factor in gram-negative bacteria
Analysis of secretion system of virulence factor in gram-negative bacteria
批准号:
19590440
负责人:
SHIMIZU Takeshi
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2008
中文摘要
点击翻译按钮获取中文摘要
英文摘要
腸管出血性大腸菌の産生する志賀毒素2(Stx2)は2種類の方法によって菌体内から、特異的に放出されることが明らかになった。一つ目の機構はstx2遺伝子が存在しているStx2ファージが特異的にファージ誘導されることによって、同調的にStx2が産生され、そのファージの容菌によってStx2も菌体外に特異的に放出される。二つ目はStx2特異的な分泌機構が存在しており、この分泌によって、Stx2が特異的に菌体外に輸送される。この過程にはStx2のBサブユニットの31番目のセリン残基が重要であった。
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
A nasal vaccine comprising B-subunit derivative of Shiga toxin 2 for cross-protection aganst Shiga toxin types 1 and 2
包含志贺毒素2的B亚基衍生物的鼻疫苗,用于针对志贺毒素1型和2型的交叉保护
DOI:
--
发表时间:
2008
期刊:
Vaccine 26
影响因子:
--
作者:
[Takao Tsuji, Takeshi Shimizu, Keiko Sasaki, Kentaro Tsukamoto, Hideyuki Arimitsu, Sadayuki Ochi, Toshiyasu Shimizu, Koki Taniguchi, Masatoshi Noda, Paola Neri, Hiroshi Mori]
通讯作者:
Hiroshi Mori
A nasal vaccine comprising B-subunit derivative of Shiga toxin 2 for cross-protection aganst Shiga toxin types 1 and 2.
一种鼻疫苗,包含志贺毒素 2 的 B 亚基衍生物,用于针对 1 型和 2 型志贺毒素的交叉保护。
DOI:
--
发表时间:
2008
期刊:
Vaccine 26
影响因子:
--
作者:
[Tatsuo Hanashima, Masami Miyake, Kinnosuke Yahiro, Yoshifumi Iwamaru, Akikazu Ando, Naoko Morinaga and Masatoshi Noda, 奈良武司訳, 奈良武司訳, Takao Tsuji]
通讯作者:
Takao Tsuji
Protection of mice from Shiga toxin-2 toxemia by mucosal vaccine of Shiga toxin 2B-His with Escheichia coli enterotoxin
大肠杆菌肠毒素志贺毒素 2B-His 粘膜疫苗对小鼠志贺毒素 2 毒血症的保护作用
DOI:
--
发表时间:
2008
期刊:
Vaccine 26
影响因子:
--
作者:
[Tatsuo Hanashima, Masami Miyake, Kinnosuke Yahiro, Yoshifumi Iwamaru, Akikazu Ando, Naoko Morinaga and Masatoshi Noda, 奈良武司訳, 奈良武司訳, Takao Tsuji, 奈良武司訳, Takao Tsuji]
通讯作者:
Takao Tsuji
Protection of mice from Shiga toxin-2 toxemia by mucosal vaccine of Shiga toxin 2B-His with Escherichia coli enterotoxin
大肠杆菌肠毒素志贺毒素 2B-His 粘膜疫苗对小鼠志贺毒素 2 毒血症的保护作用
DOI:
--
发表时间:
2008
期刊:
Vaccine 26
影响因子:
--
作者:
[Takao Tsuji, Takeshi Shimizu, Keiko Sasaki, Toshiyasu Shimizu, Kentaro Tsukamoto, Hideyuki Arimitsu, Sadayuki Ochi, Satoshi Sugiyama, Koki Taniguchi, Paola Neri, Hiroshi Mori]
通讯作者:
Hiroshi Mori
A mechanism of Stx2 release from enterohemorrahgic Escherichia coli by a non-secretion system
肠出血性大肠杆菌通过非分泌系统释放Stx2的机制
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Takeshi Shimizu, Yuko Ohta and Masatoshi Noda]
通讯作者:
Yuko Ohta and Masatoshi Noda
共 17 条
Effects of excercise continuity using motion games for groups who don't have exercise habits
-
批准号:25750344
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$1.5万
-
财政年份:2013
-
负责人:SHIMIZU Takeshi
-
依托单位:
Molecular mechanisms that function in oligodendrocyte myelination
-
批准号:24890291
-
项目类别:Grant-in-Aid for Research Activity Start-up
-
资助金额:$1.91万
-
财政年份:2012
-
负责人:SHIMIZU Takeshi
-
依托单位:
Study of Shiga toxin productions us ing in vivo analysis
-
批准号:21590478
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.08万
-
财政年份:2009
-
负责人:SHIMIZU Takeshi
-
依托单位:
Role of lipoxin as an inhibitory mediator in upper airway inflammation
-
批准号:20591999
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
-
财政年份:2008
-
负责人:SHIMIZU Takeshi
-
依托单位:
Study on the virulence factors of enterohemorrhagic Escherichia coli
-
批准号:17590382
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.37万
-
财政年份:2005
-
负责人:SHIMIZU Takeshi
-
依托单位:
Synthesis and Biological Evaluation of Antifungal Antibiotics, Spirofungin A and B
-
批准号:16590026
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:2004
-
负责人:SHIMIZU Takeshi
-
依托单位:
Prostaglandin E_2 inhibits airway inflammation
-
批准号:15591804
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.05万
-
财政年份:2003
-
负责人:SHIMIZU Takeshi
-
依托单位:
Studies for Structure-Activities Relationships of Reveromycin A : An Inhibitor of Eukaryotic Cell Growth
-
批准号:14572104
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.92万
-
财政年份:2002
-
负责人:SHIMIZU Takeshi
-
依托单位:
Synthetic Studies of Reveromycin A : An Inhibitor of Eukaryotic Cell Growth
-
批准号:12672082
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.18万
-
财政年份:2000
-
负责人:SHIMIZU Takeshi
-
依托单位:
DEVELOPMENT OF USEFUL REACTIONS USING THE NOVEL LEAVING GROUP, MONOCHLATE
-
批准号:10672015
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.11万
-
财政年份:1998
-
负责人:SHIMIZU Takeshi
-
依托单位:
Secretory cell differentiation and mucus secretion in cultures of human nasal epithelial cells.
-
批准号:08671960
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$0.64万
-
财政年份:1996
-
负责人:SHIMIZU Takeshi
-
依托单位:
Monoclonal antibodies as probes for studying human nasal secretions
-
批准号:06671710
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.41万
-
财政年份:1994
-
负责人:SHIMIZU Takeshi
-
依托单位:
Study on the establishment of a therapeutic system for severe cardiac failure by means of artificial heart as a bridge to heart transplantation
-
批准号:03454338
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$3.58万
-
财政年份:1991
-
负责人:SHIMIZU Takeshi
-
依托单位:
The relationship between human ablities of left-handed and right-handed and functional assymmetry in hemisphers of the brain. - a study is to compare musical ability of left-handed and right-handed between the Japanese and foreigner (The American) -
-
批准号:60450104
-
项目类别:Grant-in-Aid for Scientific Research (B).
-
资助金额:$0.64万
-
财政年份:1985
-
负责人:SHIMIZU Takeshi
-
依托单位:
海外基金