The nervous system structure of the bile duct in patients with choledochal cyst and a study of the neurotransmitter.

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This study analyzed the bile duct walls of patients with choledochal cyst (CBD) as to whether the nerve fibers and nerve cells in the wall are abnormal or not. Bile ducts obtained from eight patients with choledochal cyst and seven normal bile ducts without dilatation were studied. The intramural vascularity in the gallbladders of the CBD group was significantly lower than that in the control group. The rate of perivascular plexuses on the surface of intramural vessels was also significantly lower in the CBD group than in the controls. There may be a mechanism in CBD causing contractile failure and dilatation of the biliary tract as a result of decreased intramural blood flow that accompanies the diminished vascularity.