The effect on cell motility by the genes regulated by epigecetic factor
The effect on cell motility by the genes regulated by epigecetic factor
批准号:
19790935
负责人:
ARAI Makoto
金额:
$2.4万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2008
中文摘要
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英文摘要
食道癌由来培養細胞に脱メチル化剤を投与することによって、発現増加を認めた遺伝子をマイクロアレイ解析によって絞り込み、その中で、chromosome 15 open reading frame 48(C15orf48)に注目した。この遺伝子のプロモーター領域の異常メチル化を確認し、細胞運動能との関連を明らかにした。以上より、機能不明の異常メチル化により発現が制御されるC15orf48遺伝子の機能解析を行い、細胞運動能との関連性が深いことを明らかにした。
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DOI:
10.3892/or.18.2.465
发表时间:
2007-08
期刊:
Oncology reports
影响因子:
4.2
作者:
[Takashi Sugimoto;M. Arai;H. Shimada;A. Hata;N. Seki]
通讯作者:
Takashi Sugimoto;M. Arai;H. Shimada;A. Hata;N. Seki
DOI:
10.1007/s00535-008-2222-5
发表时间:
2008-09-01
期刊:
JOURNAL OF GASTROENTEROLOGY
影响因子:
6.3
作者:
[Fujiwara, Keiichi, Yasui, Shin, Yokosuka, Osamu]
通讯作者:
Yokosuka, Osamu
DOI:
10.1016/j.gie.2008.03.1065
发表时间:
2008-10-01
期刊:
GASTROINTESTINAL ENDOSCOPY
影响因子:
7.7
作者:
[Sakai, Yuzo, Eto, Reiko, Yokosuka, Osamu]
通讯作者:
Yokosuka, Osamu
DOI:
10.3892/or_00000022
发表时间:
2008-08-01
期刊:
ONCOLOGY REPORTS
影响因子:
4.2
作者:
[Arai, Makoto, Imazeki, Fumio, Yokosuka, Osamu]
通讯作者:
Yokosuka, Osamu
大腸癌由来培養細胞において脱メチル化剤投与により発現上昇したマイクロRNAの解析
结肠癌培养细胞中给予去甲基化剂后表达增加的 microRNA 分析
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[田中健史、新井誠人, 他]
通讯作者:
他
共 8 条
Molecular mechanisms of glycation exposure on the risk of developing schizophrenia
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批准号:20H03608
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Elucidation of the mechanism of renal dysfunction improvement by Kampo treatment
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Molecular mechanisms of glycative stress exposure in patients with schizophrenia
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Elucidation of molecular mechanism and prevention strategy for patient with schizophrenia based on a rare case
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批准号:15K14973
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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Evaluation of the Performance of Buoyancy-control Type Ballast-free Ship
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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Construction of molecular basis and clinical application of Kampo medicine
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Legislators and Congress as Constitutional Interpreters
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财政年份:2009
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负责人:ARAI Makoto
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依托单位:
Research on pathophysiology and mechanisms to develop carbonyl stress-related schizophrenia
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项目类别:Grant-in-Aid for Scientific Research (C)
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Research on the Safety of Liquefied Natural Gas Carriers
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批准号:19360393
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项目类别:Grant-in-Aid for Scientific Research (B)
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负责人:ARAI Makoto
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Research on Bow Slamming Load of Post-Panamax Container Ship
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依托单位:
Study on the safety assessment of free-fall lifeboat system
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批准号:12650906
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财政年份:2000
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负责人:ARAI Makoto
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依托单位:
Simulation of emergency evacuation from offshore structures and an application of virtual reality technique to analyze simulation results
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批准号:07455402
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$2.69万
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财政年份:1995
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负责人:ARAI Makoto
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依托单位:
NUMERICAL SIMULATION OF LIQUID CARGO SLOSHING IN TANKS OF FLOATING STRUCTURES
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批准号:07555609
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$3.2万
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财政年份:1995
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负责人:ARAI Makoto
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依托单位:
海外基金