Generation and application of the novel mouse model for Alzheimer's disease
Generation and application of the novel mouse model for Alzheimer's disease
批准号:
19689009
负责人:
SAITO Takashi
金额:
$11.73万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (A)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
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英文摘要
We generated two lines of the novel mouse model for Alzheimer's disease (AD), amyloid precursor protein (APP) knock-in (KI) mouse and presenilin1(PS1)-KI mouse. Each KI mice has the familial AD mutations. The mice showed relevance phenotypes rather than previous AD model mouse. These mice would be a useful tool for the prevention, the treatment and the drug discovery of AD.
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The 2nd generation mouse model for Alzheimer's disease.
第二代阿尔茨海默病小鼠模型。
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Kawakami S, Higuchi Y, Hashida M, Takashi Saito(以下4名)]
通讯作者:
Takashi Saito(以下4名)
APP-KI, a novel type mouse, for Alzheimer's disease.
APP-KI,一种新型小鼠,用于治疗阿尔茨海默病。
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[Kajiwara, M., Terada, T., Asaka, J., Aoki, M., Katsura, T., Ikai, I., Inui, K., Takashi Saito(以下4名)]
通讯作者:
Takashi Saito(以下4名)
R278I-プレセニリン1変異が持つユニークな機能
R278I-早老素1突变的独特功能
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[高橋和利, 沖田圭介, 中川誠人, 山中伸弥, 斉藤貴志(以下7名)]
通讯作者:
斉藤貴志(以下7名)
次世代型アルツハイマー病モデルマウスの作製及びその解析
下一代阿尔茨海默病模型小鼠的产生及其分析
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[Asayama M, Tamagawa M, Nakaya H, Furukawa T, Kurokawa J, Taku Okazaki, 斉藤貴志(以下4名)]
通讯作者:
斉藤貴志(以下4名)
The 2nd generation mouse mpdel for Alzheimer's Disease.
用于阿尔茨海默病的第二代小鼠 mpdel。
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Takashi Saito, et al.]
通讯作者:
et al.
共 18 条
Study for establishment of next-generation caries management method using dentin remineralization/regeneration technology
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批准号:18H02979
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.82万
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财政年份:2018
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负责人:SAITO Takashi
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依托单位:
Development of Antisense Mediated Therapy for Exons Duplication in Duchenne Muscular Dystrophy.
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批准号:25460666
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.16万
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财政年份:2013
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负责人:SAITO Takashi
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依托单位:
Tree- detentional Distribution of Radioactive Nuclide at Fuji Volcano and Fuji Volcanic Belt Caused by Fukushima Daiichi Nuclear Power Station Accident
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批准号:24510074
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.41万
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财政年份:2012
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负责人:SAITO Takashi
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依托单位:
Establishment of the diagnostics of Alzheimer' s disease using A・43
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批准号:23650185
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
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财政年份:2011
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负责人:SAITO Takashi
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依托单位:
Establishment and application of novel type of Alzheimer's disease model mouse
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批准号:23680039
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项目类别:Grant-in-Aid for Young Scientists (A)
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资助金额:$16.14万
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财政年份:2011
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负责人:SAITO Takashi
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依托单位:
A preliminary study of genetic analysis of surgical specimens from patients with focal cortical dysplasia.
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批准号:23791620
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.58万
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财政年份:2011
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负责人:SAITO Takashi
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依托单位:
Internal-organ functional construction system from stem cells by spatiotemporal pattern differentiation
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批准号:22650102
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.14万
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财政年份:2010
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负责人:SAITO Takashi
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依托单位:
Charge transfer and charge disproportionation in A-site-orderedpervoskite oxides
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批准号:22740227
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.66万
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财政年份:2010
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负责人:SAITO Takashi
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依托单位:
Development of novel material for caries treatment using mineral-inducing monomers
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批准号:21659440
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$0.99万
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财政年份:2009
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负责人:SAITO Takashi
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依托单位:
Personnel systems and incentive
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批准号:20730155
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.66万
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财政年份:2008
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负责人:SAITO Takashi
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依托单位:
Investigation for risk factors and establishment of infection control and prevention for multidrug-resistant Pseudomonas aeruginosa infection
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批准号:19790395
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.36万
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财政年份:2007
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负责人:SAITO Takashi
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依托单位:
Spatiotemporal regulation of antigen recognition and activation of T cells
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批准号:19109005
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项目类别:Grant-in-Aid for Scientific Research (S)
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资助金额:$70.22万
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财政年份:2007
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负责人:SAITO Takashi
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依托单位:
A New Analytical Application for the Inland Water Cycle by Natural Radioactive Nuclide
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批准号:19740298
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.34万
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财政年份:2007
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负责人:SAITO Takashi
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依托单位:
Development of Visual Measurement for Aqueous Pollutants Using a Thixotropic Gel
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批准号:17510074
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.46万
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财政年份:2005
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负责人:SAITO Takashi
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依托单位:
Molecular mechanism of immune suppression by negative-feedback regulation
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批准号:15390156
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.79万
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财政年份:2003
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负责人:SAITO Takashi
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依托单位:
Acquisition of Signal Information for Immune Surveillance and Determination of Immune Responses
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批准号:15078201
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$102.02万
-
财政年份:2003
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负责人:SAITO Takashi
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依托单位:
Study on visual measurement of environmental pollutants using a thixotropy gel
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批准号:14580598
-
项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
-
财政年份:2002
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负责人:SAITO Takashi
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依托单位:
Resolution of the wound healing mechanism of dertin-pulp complex and application of the knowledge on it to regenerative medicine
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批准号:14207082
-
项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$32.45万
-
财政年份:2002
-
负责人:SAITO Takashi
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依托单位:
Regulatory mechanism of T cell development by pre-T cell specific transcription factors
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批准号:13470068
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.22万
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财政年份:2001
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负责人:SAITO Takashi
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依托单位:
Experimental study of chemical transmitter of the swallowing center in the patients with dysphasia
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批准号:13672140
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.86万
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财政年份:2001
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负责人:SAITO Takashi
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依托单位:
海外基金