脳神経系発生を中心とした脂質栄養改善に関する基礎的研究

脂肪对提供必需的脂肪酸很重要。N-3多不饱和脂肪酸是体内DHA生物合成所必需的。为了了解母亲摄入n-3PUFAs对大脑发育的影响，我们用n-3PUFAs缺乏的饲料喂养雌性大鼠，雄性喂养充足的n-3PUFAs饲料，并对其后代的大脑皮层进行了几项形态学研究。我们的数据表明，适当摄入n-3多不饱和脂肪酸对大脑发育很重要。

Fat is important to provide essential fatty acid. n-3 PUFAs are necessary for DHA biosynthesis in vivo. To understand the effect of maternal intake of n-3 PUFAs on brain development, we mated female rats fed an n-3 PUFAs deficient diet with males fed an n-3 PUFAs adequate diet, and made several morphological studies of the cerebral cortices of their offspring. Our data suggest that appropriate intake of n-3 PUFAs is important for brain development.