Analysis of the mechanisms for innate immune responses to microbes
Analysis of the mechanisms for innate immune responses to microbes
批准号:
19790357
负责人:
YAMAMOTO Masahiro
金额:
$2.36万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2008
中文摘要
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英文摘要
Toll 様受容体(TLR)シグナル伝達の負の制御因子として、ユビキチン関連分子Trib1 を同定した。Trib1 を欠損するマウスを作製したところ、Trib1 欠損細胞においてTLR 刺激による炎症性サイトカインのうちIL-12p40の産生が亢進していることを見出した。また、Trib1 欠損マウス由来の細胞においては、炎症促進転写因子であるC/EBP のタンパク質量が増加しており、それが原因でC/EBP により制御されている遺伝子群の過剰発現が見られたことが考えられた。
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Role of nuclear IkappaB proteins in the regulation of host immune responses
核 IkappaB 蛋白在宿主免疫反应调节中的作用
DOI:
--
发表时间:
2008
期刊:
J Infect Chemother 14(4)
影响因子:
--
作者:
[Yamamoto M, Takeda K]
通讯作者:
Takeda K
DOI:
10.4049/jimmunol.180.6.4032
发表时间:
2008-03-15
期刊:
JOURNAL OF IMMUNOLOGY
影响因子:
4.4
作者:
[Nishimura, Junichi, Saiga, Hiroyuki, Takeda, Kiyoshi]
通讯作者:
Takeda, Kiyoshi
DOI:
10.1038/nature07240
发表时间:
2008-10-09
期刊:
NATURE
影响因子:
64.8
作者:
[Atarashi, Koji, Nishimura, Junichi, Takeda, Kiyoshi]
通讯作者:
Takeda, Kiyoshi
Toll-like receptor (TLR)アダプター分子・TRIF によるTrypanosomacruzi に対する感染防御機構
Toll样受体(TLR)接头分子/TRIF针对锥虫的感染防御机制
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[Kayama H, Ramirez-Carrozzi V, Yamamoto M, Smale S, Takeda K, 山本雅裕]
通讯作者:
山本雅裕
Stat6 independent tissue inflammation of IκBζ KO mice selective in ocular surface and perioral skin
IκBze KO 小鼠眼表和口周皮肤选择性的 Stat6 独立组织炎症
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[Ueta M, Hamuro J, Ueda E, Katoh N, Yamamoto M, Akira S, Kinoshita S]
通讯作者:
Kinoshita S
共 22 条
An analisys on the division of roles between substantive and "procedural" review of the legislative discretion.
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批准号:18K12633
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项目类别:Grant-in-Aid for Early-Career Scientists
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资助金额:$1.58万
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财政年份:2018
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负责人:YAMAMOTO Masahiro
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依托单位:
Pathogenic and genetic analysis of Toxoplasma by Japan, China and South Korea
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批准号:18KK0226
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项目类别:Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
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资助金额:$11.48万
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财政年份:2018
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负责人:YAMAMOTO Masahiro
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依托单位:
A Study in the Organizational Process of Capital Investment and M&A
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批准号:17K04074
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
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财政年份:2017
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负责人:YAMAMOTO Masahiro
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依托单位:
Reproduction of prebiotic metabolic pathways with deep-sea hydrothermal electricity
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批准号:16K05625
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2016
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负责人:YAMAMOTO Masahiro
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依托单位:
Basic research on vacuum gap insulation for ultra-high voltage devices
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批准号:16K05385
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2016
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负责人:YAMAMOTO Masahiro
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依托单位:
Deep-sea hydrothermal electricity elucidates origin of life: Proposal of Electro-Iron-Sulfur World theory
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批准号:26610188
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2014
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负责人:YAMAMOTO Masahiro
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依托单位:
Development of the in vitro maintenance system for undifferentiated stem cells using Toxoplasma ROP16
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批准号:25670201
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
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财政年份:2013
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负责人:YAMAMOTO Masahiro
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依托单位:
Mathematical studies for diffusion of contaminants
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批准号:23654030
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.25万
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财政年份:2011
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负责人:YAMAMOTO Masahiro
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依托单位:
'Environmental Electric Ecosystem', a novel biomass production system
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批准号:23760797
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.83万
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财政年份:2011
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负责人:YAMAMOTO Masahiro
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依托单位:
Elucidation of novel innate immune system by analysis of host-parasite interaction
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批准号:23689029
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项目类别:Grant-in-Aid for Young Scientists (A)
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资助金额:$17.56万
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财政年份:2011
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负责人:YAMAMOTO Masahiro
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依托单位:
Linkage between receptor for advanced glycation end-product
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批准号:22791383
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.25万
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财政年份:2010
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负责人:YAMAMOTO Masahiro
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依托单位:
Building Multidimensional Corporate Appraisal Models on the Basis of Financial Gatekeepers: A US-Japanese Comparison
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批准号:22530379
-
项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.58万
-
财政年份:2010
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负责人:YAMAMOTO Masahiro
-
依托单位:
Mathematics of inverse problems and practical solution methods
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批准号:21340021
-
项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.82万
-
财政年份:2009
-
负责人:YAMAMOTO Masahiro
-
依托单位:
Role of a nuclear protein IκBζ in innate immunity
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批准号:21790467
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.75万
-
财政年份:2009
-
负责人:YAMAMOTO Masahiro
-
依托单位:
Basic study of low emittance DC electron gun
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批准号:20740129
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.33万
-
财政年份:2008
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负责人:YAMAMOTO Masahiro
-
依托单位:
Pathophysiological research of AGEs-RAGE system and Fetuin-A on bone metabolism and arteriosclerosis
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批准号:20791039
-
项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.0万
-
财政年份:2008
-
负责人:YAMAMOTO Masahiro
-
依托单位:
Proteins for oxidation of elemental sulfur from a sulfur-oxidizing bacterium in deep-sea hydrothermal fields
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批准号:19870039
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项目类别:Grant-in-Aid for Young Scientists (Start-up)
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资助金额:$1.93万
-
财政年份:2007
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负责人:YAMAMOTO Masahiro
-
依托单位:
Mathematical analysis for inverse problems in mathematical scienes and establishment of numerical methods
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批准号:15340027
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.9万
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财政年份:2003
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负责人:YAMAMOTO Masahiro
-
依托单位:
Stability of solution and reconstruction in inverse problems
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批准号:11440025
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.55万
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财政年份:1999
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负责人:YAMAMOTO Masahiro
-
依托单位:
Sulfur isotope geochemistry of Besshi-type deposits
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批准号:08640610
-
项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.47万
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财政年份:1996
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负责人:YAMAMOTO Masahiro
-
依托单位:
海外基金