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Study on the mechanisms of human placental trophoblast syncytialisation : implication for the pathogenesis of pre-eclampsia

Study on the mechanisms of human placental trophoblast syncytialisation : implication for the pathogenesis of pre-eclampsia
人胎盘滋养层合胞化机制的研究:对先兆子痫发病机制的启示
批准号:
19591895
负责人:
KUDO Yoshiki
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009

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相关文献

中文摘要
翻译
我们已经证明CD98表面抗原,合胞素,HERV-W(人内源性逆转录病毒-W)的包膜基因,及其受体D型哺乳动物逆转录病毒受体(ASCT2)参与了合体滋养层细胞形成所需的细胞融合过程(细胞滋养层细胞系BeWo在Forsklin处理后细胞内cAMP增加)。
英文摘要
We have demonstrated that CD98 surface antigen, syncytin, an envelope gene of HERV-W (human endogenous retrovirus-W), and its receptor type D mammalian retrovirus receptor (ASCT2) are involved in the process of cell fusion necessary for syncytiotrophoblast formation using a cell model of syncytialisation (the cytotrophoblast cell line BeWo following increased intracellular cAMP by forskolin treatment).
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会议论文
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Sakashita T, Kudo Y]
通讯作者: Kudo Y
Hypoxia suppresses expression of syncytin and cell fusion during syncytialisation of human placental BeWo cells: implications for impaired trophoblast syncytialisation in pre-eclampsia
缺氧抑制人胎盘 BeWo 细胞合胞化过程中合胞素的表达和细胞融合:对先兆子痫滋养层合胞化受损的影响
DOI: --
发表时间: 2007
期刊:
影响因子: --
作者: [Nobuzane T, Kudo Y, Nobuzane T, Kudo Y]
通讯作者: Kudo Y
Effects of menopause and hormone therapy on erythrocyte deformability.
绝经和激素治疗对红细胞变形能力的影响。
DOI: --
发表时间: 2009
期刊: Menopause 16
影响因子: --
作者: [Sakashita T, Nobuzane T, Miyoshi H, Fujiwara H, Kudo Y]
通讯作者: Kudo Y
DOI: 10.1016/s0143-4004(05)80305-4
发表时间: 1992
期刊: Placenta
影响因子: 3.8
作者: [D. Evain-Brion]
通讯作者: D. Evain-Brion
共 17 条
    Cell and molecular mechanismas of placental syncytialisation: pathogenesis of preeclampsia
    • 批准号:
      17K11238
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.75万
    • 财政年份:
      2017
    • 负责人:
      KUDO Yoshiki
    • 依托单位:
    Cell and Molecular mechanisms of placental syncytialisation : implications for the pathogenesis of pre-eclampsia
    • 批准号:
      15591752
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.05万
    • 财政年份:
      2003
    • 负责人:
      KUDO Yoshiki
    • 依托单位:
    海外基金