Development and Control of Highly Efficient Catalytic Systems for Cross-and Multicomponent-Coupling Reactions

点击翻译按钮获取中文摘要

A variety of methods for carbon-carbon bond formation have been developed by the aid of transition metal catalysts, which enabled introduction of congested secondary and tertiary alkyl groups into organic molecules, multi-component coupling incorporating unsaturated hydrocarbons such as alkynes and dienes, and cross coupling via cleavage of unreactive bonds such as C-F, C-O and C-H. These successful results demonstrated potent catalytic reactivities of anionic transition metal species as key intermediates in various synthetic reaction processes. Catalytic reactions for concomitant construct of carbon-carbon bonds and carbon-heteroatom bonds and those using electronically and/or structurally flexible metal complexes were also developed.