Resistant starch type-4(RS4) as dietary fiber : evaluation of nutritional and physiological function of RS4

抗性淀粉类型4是变性淀粉，用于各种加工食品。在这项研究中，研究了RS4对消化性、发酵性、血糖和胰岛素反应、遗传性糖尿病小鼠的胰岛素抵抗和胃肠道免疫的影响。RS4对消化率、发酵性以及血糖和胰岛素反应的影响受RS4的种类和取代程度的影响。RS4延缓了2型糖尿病模型小鼠胰岛素抵抗的发展。RS4可促进小肠和盲肠中IgA的分泌。从本研究结果可以看出，RS4对代谢和胃肠免疫功能有一定的影响，是一种开发低能量食品的有用物质。

Resistant starch type 4 is modified starch and is used for various kinds of processed foods. In this study, it is examined the effects of RS4 on digestibility, fermentability, blood glucose and insulin responses, insulin resistance in genetically diabetic mice, and gastrointestinal immunity. The effect of RS4 on digestibility, fermentability and blood glucose and insulin responses were affected by the kind and degree of substitution of RS4. RS4 retarded the development of insulin resistance in a type 2 diabetes model mice. RS4 promoted secretion of IgA in the small intestine and cecum. From the results of this study, it became clear that metabolism and gastrointestinal immunity are affected by RS4, and then that RS4 is a useful material for the development of low energy food.