Influences of the occlusion on gastroesophageal reflux disease and acid clearance in oral cavity, pharynx and esophagus during sleep

点击翻译按钮获取中文摘要

In the present study, we hypothesized that good occlusion increases the acid clearance in the oral cavity, pharynx and esophagus, leading to the prohibition of the gastroesophageal reflux disease(GERD).(1) The results of the investigation of masticatory functions in patients with skeletal Class III malocclusion suggested that GERD symptoms were observed more often than in normal subjects.(2) The results of the investigation of the effects of intra-esophageal infusions of 5-mL acidic solution(0.1 N HCl) or saline to the healthy adults suggested that sleep bruxism episodes were induced by esophageal acidification.(3) Bruxism patients(n=7) had high frequency of GERD with a mild esophagitis.These researches show good occlusion has associations with esophageal acidification, suppression of upper gastrointestinal disease.