The origin and genome diversity of retroviruses causing neurological disorders

禽胶质瘤是由禽胶质瘤诱导病毒（FGV）引起的，属于禽白血病病毒（ALV-A）的A亚群。为了弄清FGV是如何以及在哪里出现的，研究人员检测了FGV在欧洲、亚洲和日本本土鸡中的流行情况，并分析了分离株的病毒基因组。结果表明，FGV可能已经出现在日本的日本家禽中，与过去在西方国家发现的家禽胶质瘤没有关系，FGV和FGV变体仍然在日本家禽中传播，显示出基因组多样性主要基于这些菌株与禽类内源性/外源性病毒之间的重组。

Fowl glioma is caused by fowl glioma-inducing virus (FGV), belonging to subgroup A of avian leucosis virus (ALV-A). To clarify how and where FGV emerged, the prevalence of FGV in European, Asian and Japanese native chickens were examined and the viral genome of the isolates were analyzed. The results suggest that FGV is likely to have appeared in Japanese fowls in Japan without a relationship to the past fowl glioma found in Western countries, and that FGV and FGV vatriants still spread in Japanese fowls, showing genome diversity mainly based on the recombination between these strains and avian endogenous/exogenous viruses.