Development of innovative genetic manipulation methods of Bifidobacterium based on the genome information.
Development of innovative genetic manipulation methods of Bifidobacterium based on the genome information.
批准号:
20510189
负责人:
SUZUKI Tohru
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
Bifidobacteria are thought to be important bacteria for human health. However, the scientific evidences has not yet obtained because it has been difficult to manipulate the gene. In this study, we developed new transformation method, selection marker and gene knock-out method based on the genome analyses.
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Construction and molecular characterization of the temperature sensitive plasmid for Bifidobacterium longum.
长双歧杆菌温度敏感质粒的构建和分子表征。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[坂口広太, 鈴木徹]
通讯作者:
鈴木徹
DOI:
10.1038/nature09646
发表时间:
2011-01-27
期刊:
NATURE
影响因子:
64.8
作者:
[Fukuda, Shinji, Toh, Hidehiro, Ohno, Hiroshi]
通讯作者:
Ohno, Hiroshi
DOI:
10.1271/bbb.80843
发表时间:
2009-06-01
期刊:
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
影响因子:
1.6
作者:
[Yasui, Kazumasa, Tabata, Mototsugu, Suzuki, Tohru]
通讯作者:
Suzuki, Tohru
DOI:
10.1093/nar/gkn884
发表时间:
2009-01
期刊:
Nucleic acids research
影响因子:
14.9
作者:
[Yasui K, Kano Y, Tanaka K, Watanabe K, Shimizu-Kadota M, Yoshikawa H, Suzuki T]
通讯作者:
Suzuki T
Expression of catalase gene affords toleranceto oxygen in Bifidobacterium longum 105 A.
过氧化氢酶基因的表达使长双歧杆菌 105 A 具有氧耐受性。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Jianlong, H., T.Suzuki]
通讯作者:
T.Suzuki
共 29 条
Establishment of bovine intestinal organoid
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Developmental control system of asymmetry of eye-sidedness and body coloration in flatfishes, and the mechanism that induces abnormality in the asymmetry development
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Control of crack propagation in textured lamination ceramics produced by electrophoretic deposition in a strong magnetic field
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Molecular control mechanism of left-right asymmetry of flounders
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Study on preparation of laminar ceramics with different oriented layers by using both magnetic and electric fields
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依托单位:
Design of novel ceramics with crystalline-oriented layers produced by electrophoretic deposition under a high magnetic field
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