Genome-wide screen and functional analysis of novel factors required for selective degradation of mitochondria
Genome-wide screen and functional analysis of novel factors required for selective degradation of mitochondria
批准号:
20570144
负责人:
OKAMOTO Koji
金额:
$3.33万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
Mitochondria serve as "the power plants of the cell", playing essential roles in cellular functions. Recently, it has been proposed that degradation of mitochondria as whole organelles, termed mitophagy, is critical for mitochondrial quality control. However, the molecular mechanisms remain largely unknown. In this study, we utilized budding yeast, and succeeded to establish selective degradation of mitochondria as a phenomenon to be analyzed, and systematically identify mitophagy-related factors.
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選択的ミトコンドリア分解:現象から分子理解へ
选择性线粒体降解:从现象到分子理解
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Ya-Jen Chang, et al., 岡本浩二]
通讯作者:
岡本浩二
Regulation of mitochondria-specific degradation in yeast.
酵母中线粒体特异性降解的调节。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[光武進, 他, 岡本浩二]
通讯作者:
岡本浩二
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[岡本浩二, 岡本徳子, 高橋郁子, 大隅良典]
通讯作者:
大隅良典
ミトコンドリア分解を司る選択的オートファジーの制御機構
选择性自噬调控线粒体降解的控制机制
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Masafumi Inoue, Takashi Konno, Kazuki Tainaka Eiji Nakata Hiro-o Yoshida Takashi Morii, Michio Shimamura, 岡本浩二]
通讯作者:
岡本浩二
選択的ミトコンドリア分解のしくみ
选择性线粒体降解机制
DOI:
--
发表时间:
2010
期刊:
医学のあゆみ 232
影响因子:
--
作者:
[M.Miyata, T.Sato, M.Mizuguchi, T.Nakamura, S.Ikemizu, Y,Nabeshima, S.Susuki, Y.Suwa, H.Morioka, Y.Ando, M.A.Suico, T.Shuto, T.koga, Y.Yamagata, H.Kai, Takashi Sato, Seiko Susuki, Masanori Miyata, 岡本浩二]
通讯作者:
岡本浩二
共 22 条
Investigation of shear force pump design for efficiency improvement and its miniaturization
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批准号:26420808
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.16万
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财政年份:2014
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负责人:OKAMOTO Koji
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依托单位:
Regulatory mechanisms and molecular bases of selective mitochondria degradation
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批准号:25291045
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.56万
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财政年份:2013
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负责人:OKAMOTO Koji
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依托单位:
Generation of an eukaryote harboring genes transferred from mitochondria to the nucleus
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批准号:25650067
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.58万
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财政年份:2013
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负责人:OKAMOTO Koji
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依托单位:
Establishmentof tools regulating mitophagyby chemical biology
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批准号:23657090
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.58万
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财政年份:2011
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负责人:OKAMOTO Koji
-
依托单位:
Regulation of cancer stem cells by MDMX/MDM2 oncoproteins
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批准号:22590299
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.33万
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财政年份:2010
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负责人:OKAMOTO Koji
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依托单位:
Study on flow-induced acoustic vibration of main steam pipe for power uprate
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批准号:22360399
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.98万
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财政年份:2010
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负责人:OKAMOTO Koji
-
依托单位:
Regulation of MDMX oncoprotein by genomic stresses
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批准号:19590295
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.25万
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财政年份:2008
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负责人:OKAMOTO Koji
-
依托单位:
Development of Radial Wave Rotor for Power Generation System in Space
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批准号:19760561
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.4万
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财政年份:2007
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负责人:OKAMOTO Koji
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依托单位:
Development of a four dimensional micro-PIV system for a non-linear fluid flow
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批准号:19206022
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$31.03万
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财政年份:2007
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负责人:OKAMOTO Koji
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依托单位:
Study on micro-dynamics in the micro-fluidic devises
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批准号:15360092
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.32万
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财政年份:2003
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负责人:OKAMOTO Koji
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依托单位:
Study on Design o fDrug Delivery System Using Assembly-deassemby Mechanicsm of Drug-inclusion Carrier
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批准号:12558110
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$5.38万
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财政年份:2000
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负责人:OKAMOTO Koji
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依托单位:
A JAPANESE-FRENCH COMPARATIVE STUDY OF CULTURAL SENSIBILITY AND COGNITIVE DEVELOPMENT ON GEOMETRICAL OBJECTS.
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批准号:02451106
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$1.66万
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财政年份:1990
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负责人:OKAMOTO Koji
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依托单位:
Purification and the mode of actions of differentiation inducing factors in a cellular slime mold
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批准号:61480010
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$2.88万
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财政年份:1986
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负责人:OKAMOTO Koji
-
依托单位:
海外基金