Construction of influenza virosome and its development to preparation of vaccine
Construction of influenza virosome and its development to preparation of vaccine
批准号:
20590033
负责人:
UENO Masaharu
金额:
$3.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
Influenza is one of the common infectious diseases caused by influenza virus. Vaccines are the most effective means to fight infectious diseases. Liposomes are known to be effective immunoadjuvants. In this article, we introduced a new method to prepare the liposome vaccine, "influenza virosomes", using inter-membrane protein transfer. We concluded that this method is useful to prepare virosomes. The virosomes showed high immunoactivity especially with MDP derivatives.
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オレイン酸のベシクル形成
油酸的囊泡形成
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[吉田湖南, 桜田剛浩, 茶木弘一, S.Chungcharoenwattana, 奥野貴士, 上野雅晴]
通讯作者:
上野雅晴
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[上野雅晴, 奥野貴士, 林京子]
通讯作者:
林京子
膜蛋白質の膜間移行を利用したインフルエンザ人工膜ワクチンの試作
利用膜蛋白的膜间转移原型生产流感人工膜疫苗
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[白石智子, 木平孝高, 林京子, 奥野貴士, 上野雅晴]
通讯作者:
上野雅晴
Vesicle Formation of Fatty Acid in the Presence of Preformed Phospholipid Vesicles
在预形成的磷脂囊泡存在下脂肪酸的囊泡形成
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Masaharu Ueno, S.Chngcharoenwattana, Takashi Okuno, Konan Yoshida]
通讯作者:
Konan Yoshida
インフルエンザビロソームの構築
流感病毒体的构建
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[萩原由希子, 白石智子, 林京子, 奥野貴士, 上野雅晴]
通讯作者:
上野雅晴
共 6 条
Efficient synthesis of functional molecules by multicomponent tandem coupling reaction and application for flow synthesis
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批准号:19K05479
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.75万
-
财政年份:2019
-
负责人:UENO Masaharu
-
依托单位:
Development of the Continuous Microflow Reaction and Multi StepProcess
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批准号:23750099
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$3.08万
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财政年份:2011
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负责人:UENO Masaharu
-
依托单位:
Development of Catalyst Immobilized Micro Reactor for Combinatorial Multi Step Reactions
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批准号:21750091
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.91万
-
财政年份:2009
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负责人:UENO Masaharu
-
依托单位:
Studies on intermembrane protein transfer and establishment of preparation method of artificial membrane vaccine
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批准号:15590039
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:2003
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负责人:UENO Masaharu
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依托单位:
Development of New Preparation Method of Artificial Membrane Vaccine Using Spontaneous Transfer of Membrane Protein
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批准号:07672311
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.47万
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财政年份:1995
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负责人:UENO Masaharu
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依托单位:
Pilot Production of Artificial Membrane Vaccine
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批准号:05807202
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.15万
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财政年份:1993
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负责人:UENO Masaharu
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依托单位:
Studies on the Factors Dominating Liposome Size, Size Distribution and Permeability
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批准号:60460218
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$2.75万
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财政年份:1985
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负责人:UENO Masaharu
-
依托单位:
New Mechod on Evaluating Fibrinolytic Activity using Calormitry
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批准号:60870079
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项目类别:Grant-in-Aid for Developmental Scientific Research
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资助金额:$1.79万
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财政年份:1985
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负责人:UENO Masaharu
-
依托单位:
海外基金