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Identification of IL-18-induced Tumor-Cell Migration Inhibitory Factor(s) and Elucidation of its Action Mechanism..

Identification of IL-18-induced Tumor-Cell Migration Inhibitory Factor(s) and Elucidation of its Action Mechanism..
IL-18诱导的肿瘤细胞迁移抑制因子的鉴定及其作用机制的阐明
批准号:
20590414
负责人:
YAMADA Naoko
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
IL-18 shows an anti-tumor action through activation of T cells and natural killer cells. We found another action of IL-18, i.e., the inhibition of metastasis by inducing the factor(s) in serum which suppresses the tumor cell mobility. In this study, we aimed to identify the tumor-cell migration inhibitory factor(s). We have revealed that IL-18 induces the factor(s) in not only serum but also the cell lysate of the liver and lung and that the factor(s) is a protein of molecular weight of less than 30,000 daltons. We have also found several candidates for the factor(s).
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会议论文
Coperative Antitumor Effects by Combined Administration α-Galactosylceramide and Interleukin-18 on Pulmonary Metastasis of Malignant Melanoma Cells.
联合使用 α-半乳糖神经酰胺和白细胞介素 18 对恶性黑色素瘤细胞肺转移的协同抗肿瘤作用。
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Naoko Yamada, et al.]
通讯作者: et al.
Differential effects of polymorphisms in the 5' flanking region of IL12RB2 on NK- and T-cell activity.
IL12RB2 5 侧翼区域多态性对 NK 细胞和 T 细胞活性的差异影响。
DOI: --
发表时间: 2008
期刊: J Interferon Cytokine Res. 28(9)
影响因子: --
作者: [Ohyama H, Kato-Kogoe N, Nishimura F, Takeuchi-Hatanaka K, Matsushita S, Yamanegi K, Yamada N, Hata M, Nakasho K, Terada N]
通讯作者: Terada N
Cooperative Antitumor Effects by Combined Administration α-Galactosylceramide and Interleukin-18 on Pulmonary Metastasis of Malignant Melanoma Cells.
联合使用 α-半乳糖神经酰胺和白细胞介素 18 对恶性黑色素瘤细胞肺转移的协同抗肿瘤作用。
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Naoko Yamada, Shoji Nishio, Hideki Ohyama, Koji Yamanegi, Keiji Nakasho, Haruki Okamura, Nobuyuki Terada]
通讯作者: Nobuyuki Terada
Enhanced suppression of pulmonary metastasis of malignant melanoma cells by combined administration of alpha- galactosylceramide and interleukin-18.
α-半乳糖神经酰胺和白细胞介素 18 联合给药可增强对恶性黑色素瘤细胞肺转移的抑制。
DOI: --
发表时间: 2008
期刊: Cancer Sci. 99(1)
影响因子: --
作者: [Nishio S, Yamada N, Ohyama H, Yamanegi K, Nakasho K, Hata M, Nakamura Y, Fukunaga S, Futani H, Yoshiya S, Ueda H, Taniguchi M, Okamura H, Terada N]
通讯作者: Terada N
20
    How the interview techniques and recording medium affect on 'fact-findings'
    • 批准号:
      19K01359
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.83万
    • 财政年份:
      2019
    • 负责人:
      YAMADA Naoko
    • 依托单位:
    Identification and the elucidation of the mechanism of interleukin 18 induced metastasis inhibitory factor(s)
    • 批准号:
      23590480
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.41万
    • 财政年份:
      2011
    • 负责人:
      YAMADA Naoko
    • 依托单位:
    Intertwining Norms and Laws on Marriage in the Dutch East Indies
    • 批准号:
      21720259
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $1.66万
    • 财政年份:
      2009
    • 负责人:
      YAMADA Naoko
    • 依托单位:
    海外基金