Development of Three-dimensional Intravascular Ultrasound Imaging for Tissue Characterization of Coronary Plaques

用于冠状动脉斑块组织表征的三维血管内超声成像的发展

• 批准号: 20590822
• 负责人: KAWASAKI Masanori
• 金额: $ 2.75万
• 依托单位: Gifu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20590822/
• 关键词: 超音波; 組織性状診断; 後方散乱波; 三次元画像; 冠動脈

With the new system, we set 512 vector lines of ultrasound signal around the circumference, whereas 256 vector lines were used in the previous system. In addition, the sampling rate of ultrasound was improved from 100MHz to 320 and 400MHz.We improved an online IB-IVUS imaging system for tissue characterization of coronary plaques. The use of the appropriate IB cutoff points for discriminating lipid pool, fibrosis and calcification resulted in tissue characterization with a high diagnostic accuracy. The thickness of fibrous cap measured by IB-IVUS was correlated with that measured by optical coherence tomography.Quantitative tissue characterization of carotid plaques using IBS ultrasound was useful to predict newly appearing ipsilateral silent ischemic lesions after carotid artery stenting.

在新系统中，我们在圆周周围设置了512条超声信号矢量线，而在以前的系统中使用了256条矢量线。此外，将超声采样频率从100 MHz提高到320和400 MHz，改进了用于冠状动脉斑块组织定征的在线IB-IVUS成像系统。使用适当的IB临界点来区分脂质池、纤维化和钙化导致组织表征具有较高的诊断准确性。IB-IVUS测量的纤维帽厚度与光学相干断层扫描测量的纤维帽厚度相关，IBS超声定量组织定征可用于预测颈动脉支架术后新发的同侧无症状缺血性病变。

项目成果

冠動脈硬化のプロセスと治療戦略IB-IVUSによる検討

IB-IVUS 检查冠状动脉硬化过程和治疗策略

• 发表时间: 2009
• 作者: Ishida T;Sun L;et al.;川崎雅規
• 通讯作者: 川崎雅規

INTEGRATED BACKSCATTER AND INTIMA-MEDIA THICKNESS OF THE THORACIC AORTA EVALUATED BY TRANSESOPHAGEAL ECHOCARDIOGRAPHY IN HYPERCHOLESTEROLEMIC PATIENTS: EFFECT OF PITAVASTATIN THERAPY

• DOI: 10.1016/j.ultrasmedbio.2008.08.011
• 发表时间: 2009-02-01
• 期刊: ULTRASOUND IN MEDICINE AND BIOLOGY
• 影响因子: 2.9
• 作者: Ono, Koji;Kawasaki, Masanori;Minatoguchi, Shinya
• 通讯作者: Minatoguchi, Shinya

Visiwave対応型Integrated Backscatter血管内超音波の開発とOCTとの比較による冠動脈プラーク線維性被膜の厚みの測定

开发Visiwave兼容集成背散射血管内超声并与OCT比较测量冠状动脉斑块纤维包膜厚度

• 发表时间: 2010
• 作者: Kashima Y;Takahashi M;Hata T;Kawaguchi M;Izawa A;Itano N;Taniguchi S;Ikeda U;川崎雅規
• 通讯作者: 川崎雅規

冠動脈IVUS・IB-IVUSの実際

冠状动脉IVUS/IB-IVUS实战

• 发表时间: 2010
• 期刊: 循環器臨床サビア「血管エコーパーフェクトガイド」
• 作者: 川崎雅規;湊口信也
• 通讯作者: 湊口信也

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