Development of Three-dimensional Intravascular Ultrasound Imaging for Tissue Characterization of Coronary Plaques

在新系统中，我们在周长周围设置了512条超声信号的矢量线，而以前的系统使用的是256条矢量线。此外，超声采样率从100 MHz提高到320 MHz和400 MHz。我们改进了用于冠状动脉斑块组织定征的在线IB-IVUS成像系统。使用适当的IB分界点来区分脂质池、纤维化和钙化，导致组织定征具有很高的诊断准确性。IB-IVUS测量的纤维帽厚度与光学相干断层成像测量的纤维帽厚度相关，IBS超声对颈动脉斑块的定量组织定征有助于预测颈动脉支架术后新出现的同侧无症状缺血性病变。

With the new system, we set 512 vector lines of ultrasound signal around the circumference, whereas 256 vector lines were used in the previous system. In addition, the sampling rate of ultrasound was improved from 100MHz to 320 and 400MHz.We improved an online IB-IVUS imaging system for tissue characterization of coronary plaques. The use of the appropriate IB cutoff points for discriminating lipid pool, fibrosis and calcification resulted in tissue characterization with a high diagnostic accuracy. The thickness of fibrous cap measured by IB-IVUS was correlated with that measured by optical coherence tomography.Quantitative tissue characterization of carotid plaques using IBS ultrasound was useful to predict newly appearing ipsilateral silent ischemic lesions after carotid artery stenting.