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Investigation of the DNA recognition mechanisms of sequence-specific LINE

Investigation of the DNA recognition mechanisms of sequence-specific LINE
序列特异性 LINE 的 DNA 识别机制研究
批准号:
20770085
负责人:
MAITA Nobuo
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
The final goal of this project was to obtain the crystal structure of LINE-EN : DNA to reveal how LINE-EN to bind to DNA and cleave it, but it was not completed. During the optimization for crystallization, I found that LINE-EN would form a dimer in solution, and that EN alone is not enough to make the stable complex with DNA and necessary a Myb-like domain located just downstream of EN.
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会议论文
DOI: 10.1074/jbc.m109.078717
发表时间: 2010-03-26
期刊: JOURNAL OF BIOLOGICAL CHEMISTRY
影响因子: 4.8
作者: [Fujiwara, Kazuko, Maita, Nobuo, Taniguchi, Hisaaki]
通讯作者: Taniguchi, Hisaaki
DOI: 10.1074/jbc.m109.081752
发表时间: 2010-02-12
期刊: JOURNAL OF BIOLOGICAL CHEMISTRY
影响因子: 4.8
作者: [Maita, Nobuo, Nyirenda, James, Kohda, Daisuke]
通讯作者: Kohda, Daisuke
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
Crystal structure of aminomethyltransferase in complex with dihydrolipoyl-H-protein of the glycine cleavage system
氨甲基转移酶与甘氨酸裂解系统的二氢硫辛酰-H-蛋白复合物的晶体结构
DOI: --
发表时间: 2010
期刊: Journal of Biological Chemistry
影响因子: 4.8
作者: [Okamura-Ikeda, K., et al.]
通讯作者: et al.
Development of protein crystallization tag using crystalline lattice
  • 批准号:
    15K13747
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
  • 资助金额:
    $2.5万
  • 财政年份:
    2015
  • 负责人:
    MAITA Nobuo
  • 依托单位:
Investigation into the LINE transposition process by structural study of DNA-protein complexes
  • 批准号:
    23570139
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.49万
  • 财政年份:
    2011
  • 负责人:
    MAITA Nobuo
  • 依托单位:
海外基金