Investigation of the DNA recognition mechanisms of sequence-specific LINE
Investigation of the DNA recognition mechanisms of sequence-specific LINE
批准号:
20770085
负责人:
MAITA Nobuo
金额:
$2.66万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
关键词:
中文摘要
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英文摘要
The final goal of this project was to obtain the crystal structure of LINE-EN : DNA to reveal how LINE-EN to bind to DNA and cleave it, but it was not completed. During the optimization for crystallization, I found that LINE-EN would form a dimer in solution, and that EN alone is not enough to make the stable complex with DNA and necessary a Myb-like domain located just downstream of EN.
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DOI:
10.1074/jbc.m109.078717
发表时间:
2010-03-26
期刊:
JOURNAL OF BIOLOGICAL CHEMISTRY
影响因子:
4.8
作者:
[Fujiwara, Kazuko, Maita, Nobuo, Taniguchi, Hisaaki]
通讯作者:
Taniguchi, Hisaaki
DOI:
10.1074/jbc.m109.081752
发表时间:
2010-02-12
期刊:
JOURNAL OF BIOLOGICAL CHEMISTRY
影响因子:
4.8
作者:
[Maita, Nobuo, Nyirenda, James, Kohda, Daisuke]
通讯作者:
Kohda, Daisuke
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氨甲基转移酶与甘氨酸裂解系统的二氢硫辛酰-H-蛋白复合物的晶体结构
DOI:
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4.8
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2011
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Nature Structural & Molecular Biology
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16.8
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批准号:15K13747
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项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.5万
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财政年份:2015
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负责人:MAITA Nobuo
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依托单位:
Investigation into the LINE transposition process by structural study of DNA-protein complexes
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批准号:23570139
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.49万
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财政年份:2011
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负责人:MAITA Nobuo
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依托单位:
海外基金