课题基金 / 基金详情

Development of an assessment system of probiotics based on host-microbial crosstalk information

Development of an assessment system of probiotics based on host-microbial crosstalk information
基于宿主-微生物串扰信息的益生菌评估系统的开发
批准号:
20780105
负责人:
FUKUDA Shinji
金额:
$2.75万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009

项目摘要

项目成果

FUKUDA Shinji的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
To elucidate the prevention mechanisms by probiotic bifidobacteria against E. coli O157:H7 lethal infection, we took advantage of multi-omics-based approach. Detailed research revealed that the fecal concentration of short chain fatty acid (SCFA) in probiotic bifidobacteria-associated mice was significantly higher than that in non-probiotic bifidobacteria-associated mice. SCFA could inhibit colonic epithelial cells from cell death provoked by O157 infection, suggesting that the abilities of sugar metabolism and SCFA production in probiotic bifidobacteria play a critical role in the prevention of O157 lethal infection.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
網羅的解析手法による宿主-腸内フローラ間相互作用の解明
使用综合分析方法阐明宿主-肠道菌群相互作用
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [福田真嗣, 大野博司]
通讯作者: 大野博司
腸管バリア機能改善剤
肠屏障功能改善剂
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: []
通讯作者:
DOI: 10.1371/journal.pone.0004893
发表时间: 2009
期刊: PloS one
影响因子: 3.7
作者: [Fukuda S, Nakanishi Y, Chikayama E, Ohno H, Hino T, Kikuchi J]
通讯作者: Kikuchi J
Gut environment assessment system based on multiple omics approach
基于多组学方法的肠道环境评估系统
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Fukuda, S., Date, Y., Kato, T., Nakanishi, Y., Chikayama, E., Tsuboi, Y., Tsuneda, S., Moriya, S., Kikuchi, J., Ohno, H.]
通讯作者: H.
21
    A Study of Characteristics and Diversity of Ricardo Studies in Japan
    • 批准号:
      15K03376
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.66万
    • 财政年份:
      2015
    • 负责人:
      FUKUDA Shinji
    • 依托单位:
    Development of fundamental technology for gut ecosystem regulation towards preventive and therapeutic medicine
    • 批准号:
      26660118
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.5万
    • 财政年份:
      2014
    • 负责人:
      FUKUDA Shinji
    • 依托单位:
    Construction of novel platform for development of functional food products based on next-generation integrated omics approach
    • 批准号:
      24658129
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.66万
    • 财政年份:
      2012
    • 负责人:
      FUKUDA Shinji
    • 依托单位:
    Exploring the gut microbiota-derived immunomodulation factors
    • 批准号:
      24380072
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.56万
    • 财政年份:
      2012
    • 负责人:
      FUKUDA Shinji
    • 依托单位:
    海外基金