Role of the membrane-anchored growth factor in the cell cycle regulation of cancer stem cells
Role of the membrane-anchored growth factor in the cell cycle regulation of cancer stem cells
批准号:
20790259
负责人:
FUKUDA Shinji
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009
中文摘要
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英文摘要
Recent studies suggests that tumors arise from cancer stem cells. Here, we focused on a membrane-anchored growth factor, Amphiregulin (AREG), which is thought to be expressed in side-population (SP) of hepatocyte cell line, Huh7. We identified AREG-regulating protein (ARP), whose expression is also detected in Huh7 SP. ARP promotes the production of soluble AREG (N-terminal fragment of AREG), thus might be involved in the cell cycle regulation of hepatocyte stem cell regulation.
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ADAMによる膜型増殖因子sheddingとcell cycle制御
ADAM 的膜生长因子脱落和细胞周期控制
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Yano S, Wang W, Li Q, Matsumoto K, Sakurama H, Nakamura T, Ogino H, Kakiuchi S, Hanibuchi M, Nishioka Y, Uehara H, Mitsudomi T, Yatabe Y, Nakamura T, Sone S., Tanuma N, 酒井寿郎, 古川貴久, 福田信治]
通讯作者:
福田信治
Gene expression analyses on embryonic external genitalia : identification of regulatory genes possibly involved in masculinization processes
胚胎外生殖器的基因表达分析:鉴定可能参与男性化过程的调节基因
DOI:
--
发表时间:
2008
期刊:
Congenital Anomalies 48
影响因子:
--
作者:
[Nishida H, Miyagawa S, Matsumaru D, Wada Y, Satoh Y, Ogino Y, Fukuda S, Iguchi T, Yamada G.]
通讯作者:
Yamada G.
Ectodomain shedding of EGF family members - the molecular mechanism and the physiological roles-
EGF家族成员的胞外域脱落-分子机制和生理作用-
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[井上博文, 中山寛尚, 上谷晃由, 福田信治, 東山繁樹]
通讯作者:
東山繁樹
膜貫通型増殖因子amphiregulinのshedding制御機構の解析
跨膜生长因子双调蛋白脱落控制机制分析
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[中山寛尚, 福田信治, 井上博文, 東山繁樹]
通讯作者:
東山繁樹
分子生物学イラストレイテッド
分子生物学图解
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[柳原克彦, 仁木宏典]
通讯作者:
仁木宏典
共 9 条
A Study of Characteristics and Diversity of Ricardo Studies in Japan
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批准号:15K03376
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.66万
-
财政年份:2015
-
负责人:FUKUDA Shinji
-
依托单位:
Development of fundamental technology for gut ecosystem regulation towards preventive and therapeutic medicine
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批准号:26660118
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
-
财政年份:2014
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负责人:FUKUDA Shinji
-
依托单位:
Construction of novel platform for development of functional food products based on next-generation integrated omics approach
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批准号:24658129
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.66万
-
财政年份:2012
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负责人:FUKUDA Shinji
-
依托单位:
Exploring the gut microbiota-derived immunomodulation factors
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批准号:24380072
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.56万
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财政年份:2012
-
负责人:FUKUDA Shinji
-
依托单位:
Role of growth factor and cytokine singaling in the determination of mammary epithelial cell characteristics
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批准号:24590382
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.41万
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财政年份:2012
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负责人:FUKUDA Shinji
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依托单位:
A Study of Differences between Ricardo Studies in Japan and in the West
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批准号:22530193
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.25万
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财政年份:2010
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负责人:FUKUDA Shinji
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依托单位:
Identification and assessment of probiotic factor(s) via multiple omics approach.
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批准号:22780132
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.5万
-
财政年份:2010
-
负责人:FUKUDA Shinji
-
依托单位:
Analysis of the machinery of ectodomain shedding and its possible role for the action of HB-EGF
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批准号:22790319
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.5万
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财政年份:2010
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负责人:FUKUDA Shinji
-
依托单位:
Fish habitat evaluation systems considering spatiotemporal dynamics
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批准号:21780225
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项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.83万
-
财政年份:2009
-
负责人:FUKUDA Shinji
-
依托单位:
Development of an assessment system of probiotics based on host-microbial crosstalk information
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批准号:20780105
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.75万
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财政年份:2008
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负责人:FUKUDA Shinji
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依托单位:
Development of fish habitat preference model using hybrid artificial intelligence techniques
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批准号:19880023
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项目类别:Grant-in-Aid for Young Scientists (Start-up)
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资助金额:$1.67万
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财政年份:2007
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负责人:FUKUDA Shinji
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依托单位:
Examination of the neurological mechanism of grammatical impairment through a linguistic investigation of specific language impairment
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批准号:15520266
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.73万
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财政年份:2003
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负责人:FUKUDA Shinji
-
依托单位:
海外基金