The strategy to avoid the side effect of lipid-lowering agents
The strategy to avoid the side effect of lipid-lowering agents
批准号:
20790126
负责人:
KOBAYASHI Masaki
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009
中文摘要
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英文摘要
In this study, we focused on a nuclear receptor, LXR (liver X receptor) and examined the effect of statins, lipid-lowering agents, on LXR function in HepG2 cells and the rat liver. Therefore this study can lead to precise drug therapy of hyperlipidemia.
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スタチン系薬物による肝ATP-binding cassette transporter A1(ABCA1)発現に及ぼす影響
他汀类药物对肝脏 ATP 结合盒转运蛋白 A1 (ABCA1) 表达的影响
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[合田圭祐, 小林正記, 知嵜郁美, 板垣史郎, 井関健]
通讯作者:
井関健
receptor regulates expression of MRP2 but not that of MDR1 and BCRP in the liver. Biochim.
受体调节肝脏中 MRP2 的表达,但不调节 MDR1 和 BCRP 的表达。
DOI:
--
发表时间:
2009
期刊:
Biophys. Acta 1788(11)
影响因子:
--
作者:
[Chisaki, I., Kobayashi, M., Itagaki, S., Hirano, T. Iseki, K. Liver X]
通讯作者:
K. Liver X
スタチン系薬物による肝ATP-binding cassette transporter A1 (ABCA1)発現に及ぼす影響
他汀类药物对肝脏 ATP 结合盒转运蛋白 A1 (ABCA1) 表达的影响
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[合田圭佑, 小林正紀, 知嵜郁美, 板垣史郎, 井関健]
通讯作者:
井関健
肝MRP2発現に与えるスタチン系薬物の影響
他汀类药物对肝脏MRP2表达的影响
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[知嵜郁美、小林正紀、板垣史郎, 平野剛, 井関健]
通讯作者:
井関健
DOI:
10.1016/j.bbamem.2009.08.014
发表时间:
2009-11-01
期刊:
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
影响因子:
3.4
作者:
[Chisaki, Ikumi, Kobayashi, Masaki, Iseki, Ken]
通讯作者:
Iseki, Ken
Study on ultrasound tagged optical tomography based on chemiluminescence enhancement effect
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批准号:17K01368
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
-
财政年份:2017
-
负责人:KOBAYASHI Masaki
-
依托单位:
The strategy to avoid drug-induced skeletal muscle injury involved in monocarboxylate transporter
-
批准号:24790138
-
项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.91万
-
财政年份:2012
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负责人:KOBAYASHI Masaki
-
依托单位:
The elucidation of physiological functions of transcription factor FoxO1 in pancreatic alpha cell
-
批准号:23791013
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.66万
-
财政年份:2011
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负责人:KOBAYASHI Masaki
-
依托单位:
Development of sentinel-lymphnode imaging system by ultrasonic tagging fluorescence imaging technique
-
批准号:22500440
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.66万
-
财政年份:2010
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负责人:KOBAYASHI Masaki
-
依托单位:
The roles of transcription factor FoxO1 in pancreatic β cell proliferation and neogenesis
-
批准号:21790862
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.75万
-
财政年份:2009
-
负责人:KOBAYASHI Masaki
-
依托单位:
Development of the fluorescence imaging system for medical applications based on the ultrasonic tagging technique
-
批准号:19300162
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$7.9万
-
财政年份:2007
-
负责人:KOBAYASHI Masaki
-
依托单位:
Study on the imaging technique of fluorescent marker and reporter to extract biological function and gene expression base on the ultrasound tagging fluorescence detection method
-
批准号:17500314
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.11万
-
财政年份:2005
-
负责人:KOBAYASHI Masaki
-
依托单位:
Study on the development of real-time and in vivo measurement technique of gene expression on mice using optical methods.
-
批准号:15500322
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:2003
-
负责人:KOBAYASHI Masaki
-
依托单位:
海外基金