Roles of the serotonin synthesis emzyme, TphD2, in body patterning

血清素合成酶 TphD2 在身体模式中的作用

• 批准号: 20870024
• 负责人: MAEGAWA Shingo
• 金额: $ 2.11万
• 依托单位: Kyoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (Start-up)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20870024/
• 关键词: 胚葉形成; 原腸形成; 体節形成; 胚発生; セロトニン; 形態形成

I found the following facts with zebrafish embryos. 1. Inhibitors of tryptophan hydroxylase or the antidepressant, Prozac, affected convergence during the body patterning. 2. A serotonin transporter, serta, which is the target for Prozac, is expressed during gastrulation. 3. Gastrula embryos produced serotonin. Based on the findings, I conclude that serotonin is involved in regulation of convergence movements during body patterning.

我在斑马鱼胚胎中发现了以下事实。1.色氨酸羟化酶抑制剂或抗抑郁药百忧解影响身体模式的收敛。2.血清素转运蛋白serta是百忧解的靶点，在原肠胚形成期间表达。3.原肠胚产生血清素。基于这些发现，我得出结论，血清素参与调节收敛运动在身体模式。

项目成果

Roles of tryptophan hydroxylase in zebrafish embryogenesis.

色氨酸羟化酶在斑马鱼胚胎发生中的作用。

• 发表时间: 2009
• 作者: Shingo Maegawa;Hiroshi Hosokawa;Eric S. Weinberg;Shigeo Kobayahsi
• 通讯作者: Shigeo Kobayahsi

Serotonin in involved in zebrafish body patterning

血清素参与斑马鱼的身体图案

• 发表时间: 2009
• 作者: Shingo Maegawa;Hiroshi Hosokawa;Eric S. Weinberg;Shigeo Kobayahsi
• 通讯作者: Shigeo Kobayahsi

Roles of tryptophan hydroxylase in early development

色氨酸羟化酶在早期发育中的作用

• 发表时间: 2008
• 作者: Shingo Maegawa;Hiroshi Hosokawa;Eric S. Weinberg;Shigeo Kobayashi
• 通讯作者: Shigeo Kobayashi

A novel application of metabolomics in vertebrate development

• DOI: 10.1016/j.bbrc.2009.06.041
• 发表时间: 2009-08-14
• 期刊: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
• 影响因子: 3.1
• 作者: Hayashi, Shunsuke;Akiyama, Shinichi;Fukusaki, Eiichiro
• 通讯作者: Fukusaki, Eiichiro

Roles of Tryptophan Hydroxylase in Early Developmant

色氨酸羟化酶在早期发育中的作用

• 发表时间: 2008
• 作者: 前川真吾;細川浩;Eric S. Weinberg;小林茂夫;前川真吾;前川真吾;前川真吾;前川真吾
• 通讯作者: 前川真吾