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Neural transmission abnormality in focal dystonia-focusing on dopaminergic and adenosine systems

Neural transmission abnormality in focal dystonia-focusing on dopaminergic and adenosine systems
局灶性肌张力障碍的神经传递异常——聚焦多巴胺能和腺苷系统
批准号:
20591038
负责人:
ISHII Kenji
金额:
$3.0万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
The purpose of this study was to investigate the pathophysiological mechanism of focal dystonia with Positron Emission Tomography and Magnetic Resonance Imaging for the development of effective treatment. We examined the brains of essential blepharospasm (EBS) patients and found that the dopamine D_2 receptor density was declined, the glucose metabolism in the thalamus was elevated in patients with photophobia, Adenosine A_1 receptor density was unremarkable in the striatum, and the gray matter density in the primary sensory-motor cortex in the face region was increased. These findings suggest the functional abnormality in the brain of focal dystonia patients.
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被殻アデノシンA1 受容体分布の加齢変化-[C-11]MPDX PETを用いた検討-
壳核腺苷 A1 受体分布的年龄相关变化 - 使用 [C-11]MPDX PET 进行的研究 -
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [三品雅洋, 石井賢二, 木村裕一, 坂田宗之, 織田圭一, 小林士郎, 片山泰朗, 石渡喜一]
通讯作者: 石渡喜一
目と視覚の不定愁訴・不明愁訴
眼睛和视力的不确定/未明确的主诉
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [若倉雅登, 清澤源弘, 山田昌和, ほか]
通讯作者: ほか
DOI: 10.1111/j.1600-0404.2008.01053.x
发表时间: 2009-01-01
期刊: ACTA NEUROLOGICA SCANDINAVICA
影响因子: 3.5
作者: [Horie, C., Suzuki, Y., Ishii, K.]
通讯作者: Ishii, K.
The pre-supplementary and primary motor areas generate rhythm for voluntary eye opening and closing movements.
前辅助运动区和主要运动区产生自愿睁眼和闭眼运动的节奏。
DOI: --
发表时间: 2010
期刊: Tohoku J Exp Med. 222
影响因子: --
作者: [Suzuki Y, Kiyosawa M, Mochizuki M, Ishiwata K, Ishii K.]
通讯作者: Ishii K.
13
    Research on the management of reiens and ossuary halls run by religious corporations-focusing on "name lending"
    • 批准号:
      18K00081
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.5万
    • 财政年份:
      2018
    • 负责人:
      ISHII Kenji
    • 依托单位:
    Dynamical charge correlation of strongly correlated electrons studied by resonant inelastic scattering of synchrotron x-rays
    Research about space transformation and the publicity of the precincts place of religious corporation
    • 批准号:
      15K02058
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.91万
    • 财政年份:
      2015
    • 负责人:
      ISHII Kenji
    • 依托单位:
    Observation of magnetic excitations in 5d transition metal oxides by resonant inelastic scattering of synchrotron radiation x-rays
    • 批准号:
      23740246
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.83万
    • 财政年份:
      2011
    • 负责人:
      ISHII Kenji
    • 依托单位:
    海外基金