Predictors of side effects induced by second generation antipsychotics

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1) Dysregulation of the adipocytokines may have already occurred before subjects undergoing treatment with second-generation antipsychotic agents exhibit impaired fasting glucose.2) 9-OH-risperidone (RIS) is considered to play a more important role in prolactin (PRL) elevation than RIS, and a gender difference exists in the effect of 9-OH-RIS on PRL level.3) The mean QTcF in the RIS group was significantly longer than that of the olanzapine and control groups during nighttime.