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Analysis of endocrine-related protein involved in prostate cell growth

Analysis of endocrine-related protein involved in prostate cell growth
前列腺细胞生长相关内分泌相关蛋白的分析
批准号:
20591869
负责人:
TAKAHASHI Satoru
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
(1) We demonstrated the differential expression of estrogen receptor-related protein in prostate cancer. (2) We evaluated CYP3A4 expression in human prostrate cancer tissues. (3) We identified amyloid precursor protein and ARFGAP3 as a primary androgen targetandrogen target genes that are directly regulated by AR in LNCaP cells, by combining chromatin immunoprecipitation (ChIP) with tiling micro-arrays (ChIP-chip). (4) We identified Oct1 correlates with the poorer survival prognosis of the prostate cancer patients.
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ARFGAP3 is an androgen-responsive gene that positively promotes proliferation in prostate cancer cell line.
ARFGAP3 是一种雄激素反应基因,可积极促进前列腺癌细胞系的增殖。
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [大日方大亮, 高山賢一, 浦野友彦, 堀江公仁子, 池田和博, 大内尉義, 高橋悟, 井上聡, 大日方大亮]
通讯作者: 大日方大亮
DOI: 10.1111/j.1349-7006.2009.01451.x
发表时间: 2010-03-01
期刊: CANCER SCIENCE
影响因子: 5.7
作者: [Fujimura, Tetsuya, Takahashi, Satoru, Inoue, Satoshi]
通讯作者: Inoue, Satoshi
Differential expression of estrogen-related receptors beta and gamma (ERRbeta and ERRgamma) and their clinical significance in human prostate cancer
雌激素相关受体β和γ(ERRbeta和ERRgamma)的差异表达及其在人类前列腺癌中的临床意义
DOI: --
发表时间: 2010
期刊: Cancer Sci 101
影响因子: --
作者: [Meshima, K., 石原宏, Ikeda K, Fujimura T]
通讯作者: Fujimura T
DOI: 10.1016/j.urology.2009.02.033
发表时间: 2009-08-01
期刊: UROLOGY
影响因子: 2.1
作者: [Fujimura, Tetsuya, Takahashi, Satoru, Inoue, Satoshi]
通讯作者: Inoue, Satoshi
10
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