A role of MMP family molecules in remodeling ECM and advancing calcification
A role of MMP family molecules in remodeling ECM and advancing calcification
批准号:
20592134
负责人:
SASANO Yasuyuki
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
An organ culture system to model the physiological calcification process was designed using rat embryonic calvaria as a device for analyzing its mechanism. Standardized calvarial explants were dissected from rat embryos aged day 18 and cultured for 1, 3, and 5 days. The Ca content was examined with atomic absorption spectrophotometry and distribution of Ca and the concentration of Ca, P and C were examined with von Kossa stain and/or SEM-EDX. The result indicates that the organ culture system using E18 calvaria is useful for modeling of the physiological calcification process in vitro.
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The physiological calcification process is replicated in a rat embryonic calvarial culture.
在大鼠胚胎颅盖培养物中复制生理钙化过程。
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Kimura Y, Kikunaga S, Takahashi I, Hatakeyama Y. Fukumoto S, Sasano Y]
通讯作者:
Sasano Y
カプサイシンの全身投与が知覚および三叉神経線維の形態に及ぼす影響
全身施用辣椒素对感觉知觉和三叉神经纤维形态的影响
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[加藤晶子、中村恵, 他]
通讯作者:
他
Immunohistochemical localization of the STRO-1 antigen in developing rat teeth by light microscopy and electron microscopy.
通过光学显微镜和电子显微镜对发育中的大鼠牙齿中 STRO-1 抗原进行免疫组织化学定位。
DOI:
--
发表时间:
2009
期刊:
J Electron Microsc 58(6)
影响因子:
--
作者:
[Kaneko R, Akita H, Shimauchi H, Sasano Y]
通讯作者:
Sasano Y
Bone formation and ECM remodeling cease within a limited period regardless of completion of bone healing in the rat calvarial defect.
无论大鼠颅骨缺损是否完成骨愈合,骨形成和 ECM 重塑都会在有限时间内停止。
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[安藤浩二, 他, Sasano Y]
通讯作者:
Sasano Y
DOI:
10.1111/j.1601-0825.2009.01522.x
发表时间:
2009-05-01
期刊:
ORAL DISEASES
影响因子:
3.8
作者:
[Ebina, H., Hatakeyama, J., Sasano, Y.]
通讯作者:
Sasano, Y.
共 25 条
Expression and involvement of the novel extracellular -matrix-degrading enzymes ADAMTS during osteogenesis and bone regeneration.
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批准号:15390550
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.15万
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财政年份:2003
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负责人:SASANO Yasuyuki
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依托单位:
Regulatory mechanisms for degradation of extracellular matrix duning cementogenesis
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批准号:13671893
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.54万
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财政年份:2001
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负责人:SASANO Yasuyuki
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依托单位:
Expression of genes and proteins of extracellular matrix molecules during differentiation of cementum and alveolar bone
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批准号:11671794
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.92万
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财政年份:1999
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负责人:SASANO Yasuyuki
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依托单位:
Involvement of cell-cell and cell-matrx adhesion molecules in chondroblastic and osteoblasticdifferentiation
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批准号:09671844
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.73万
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财政年份:1997
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负责人:SASANO Yasuyuki
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依托单位:
国内基金
海外基金
板栗采后“石灰化”发生机理研究
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批准号:30871760
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项目类别:面上项目
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资助金额:34.0万元
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批准年份:2008
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负责人:顾采琴
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依托单位: