The functional roles of IL-10 in periapical inflammation
The functional roles of IL-10 in periapical inflammation
批准号:
20592222
负责人:
SUZUKI Noriyuki
金额:
$2.91万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
The periapical lesion is a granuloma containing a mixed inflammatory infiltrate induced by local immune reaction, however, its pathogenesis and the mechanism of expansion are still unclear. In this study, we examined the roles of IL-10 and Th1 cytokines in periapical inflammation using knockout (KO) mice. We conclude that IL-12-dependent T cell-mediated responses seem to induce hyper periapical inflammation in IL-10 KO mice.
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Protective role of osteopontin in endodontic infection.
骨桥蛋白在牙髓感染中的保护作用。
DOI:
10.1111/j.1365-2567.2009.03159.x
发表时间:
2010
期刊:
Immunology
影响因子:
6.4
作者:
[Rittling,SusanR, Zetterberg,Craig, Yagiz,Kader, Skinner,Stephen, Suzuki,Noriyuki, Fujimura,Akira, Sasaki,Hajime]
通讯作者:
Sasaki,Hajime
VIP receptor expression in tooth development
VIP受体在牙齿发育中的表达
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Xu J, Kawashima N, Suzuki N, Okuhara S, Wei S, Takahashi S, Zhou M, Koizumi Y, Suda H]
通讯作者:
Suda H
TL-10ノックアウトマウスに誘発した根尖性歯周炎におけるIL-12の役割
IL-12 在 TL-10 敲除小鼠诱导的根尖牙周炎中的作用
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[鈴木規元, 川島伸之, 須田英明]
通讯作者:
須田英明
Promotive effects of Sp7 on Dspp expression
Sp7对Dspp表达的促进作用
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[N Kawashima, J Xu, T Iwata, S Takahashi, Y Koizumi, K Takimoto, Z Mengyu, C Ohi, N Suzuki, T Sugiyama, H Suda]
通讯作者:
H Suda
Effective suppression of periapical lesion expansion by Cathepsin K inhibitor
组织蛋白酶 K 抑制剂有效抑制根尖周病变扩大
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Suzuki N, Kawashima N, Xu J, Suda H.]
通讯作者:
Suda H.
共 12 条
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