Health promotional effects of the combination of supplementation and exercise in old mice having various genetic backgrounds

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This study is a basic medical research that analyzed health promotional effects of the short-term combination of nutrient supply and high-intensity interval walking exercise in old mice having various genetic backgrounds. We found that high-levels of fasting blood glucose in mice were improved after the intervention of supplementation with flavonoids and exercise for only three weeks, and that the combination of supplementation and exercise had a good effect for obesity compared with exercise alone. We have to investigate a dose of nutrient, an interventional period, an optimal route, and the molecular mechanism, but we believe that these findings and strategies are useful to help the health promotion for the elderly person.